Biomedical Research Foundation Academy Of AthensAcademy Of Athens
Research Highlights

2021
RASSF1A disrupts the NOTCH signaling axis via SNURF/RNF4-mediated ubiquitination of HES1 RASSF1A disrupts the NOTCH signaling axis via SNURF/RNF4-mediated ubiquitination of HES1

Vassilis G. Gorgoulis and colleagues recently published a study in EMBO Reports

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Reconstituted HDL-apoE3 promotes endothelial cell migration through ID1 and its downstream kinases ERK1/2, AKT and p38 MAPK Reconstituted HDL-apoE3 promotes endothelial cell migration through ID1 and its downstream kinases ERK1/2, AKT and p38 MAPK

Despina Sanoudou and colleagues recently published a paper in Metabolism - Clinical and Experimental

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CD103 integrin identifies a high IL-10-producing FoxP3+ regulatory T-cell population suppressing allergic airway inflammation CD103 integrin identifies a high IL-10-producing FoxP3+ regulatory T-cell population suppressing allergic airway inflammation

Evangelos Andreakos, Sofia Tagkareli and colleagues recently published a study in Allergy

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The effect of S427F mutation on RXRα activity depends on its dimeric partner The effect of S427F mutation on RXRα activity depends on its dimeric partner

Apostolos Klinakis, Zoe Cournia and colleagues recently published a study in Chemical Science

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N-terminal domain mutations of the spike protein are structurally implicated in epitope recognition in emerging SARS-CoV-2 strains. N-terminal domain mutations of the spike protein are structurally implicated in epitope recognition in emerging SARS-CoV-2 strains.

Theodoros Rampias, Apostolos Klinakis and Zoe Cournia recently published a study in Computational and Structural Biotechnology Journal

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Nuclear receptor NR5A2 negatively regulates cell proliferation and tumor growth in nervous system malignancies Nuclear receptor NR5A2 negatively regulates cell proliferation and tumor growth in nervous system malignancies

Panagiotis Politis, Dimitris Gkikas and colleagues recently published a study in PNAS

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Activin-A impedes the establishment of CD4+ T cell exhaustion and enhances anti-tumor immunity in the lung Activin-A impedes the establishment of CD4+ T cell exhaustion and enhances anti-tumor immunity in the lung

Maria Semitekolou, Georgina Xanthou and colleagues recently published a paper in Journal of Experimental and Clinical Cancer Research

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Prox1 inhibits neurite outgrowth during central nervous system development Prox1 inhibits neurite outgrowth during central nervous system development

Panagiotis Politis, Valeria Kaltezioti and colleagues recently published a study in Cellular and Molecular Life Sciences

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Regulatory T cell transcriptomic reprogramming characterizes adverse events by checkpoint inhibitors in solid tumors Regulatory T cell transcriptomic reprogramming characterizes adverse events by checkpoint inhibitors in solid tumors

Panayotis Verginis, Themis Alissafi and colleagues recently published a study in Cancer Immunology Research

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A Novel SNCA A30G Mutation Causes Familial Parkinson's Disease A Novel SNCA A30G Mutation Causes Familial Parkinson's Disease

Leonidas Stefanis and colleagues recently published a paper in Movement Disorders

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A switch in pdgfrb+ cell-derived ECM composition prevents inhibitory scarring and promotes axon regeneration in the zebrafish spinal cord A switch in pdgfrb+ cell-derived ECM composition prevents inhibitory scarring and promotes axon regeneration in the zebrafish spinal cord

Dimitris Beis, Vasiliki Tsata and colleagues recently published a manuscript in Developmental Cell

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