Biomedical Research Foundation Academy Of AthensAcademy Of Athens
Research Highlights :18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomographic Imaging Detects Aortic Wall Inflammation in Patients With Repaired Coarctation of Aorta

 

Constantinos Anagnostopoulos and colleagues recently published a paper in Circulation Cardiovascular Imaging

 

Aortic 18F-fluorodeoxyglucose (FDG) uptake from PET/CT scans could flag sustained inflammation in patients with surgically repaired coarctation of aorta late during adult life, in the absence of risk factors for coronary artery disease. Increased 18F-FDG uptake in the aorta can be  a novel biomarker predictive of aortopathy or hypertension development at a later stage in these subjects.

 


Aortic 18F-fluorodeoxyglucose (18F-FDG) uptake by positron emission tomography/computed tomographic (PET/CT) imaging in adult patients with repaired coarctation of aorta (RCoA) and control subjects. Representative PET/CT images of aortic 18F-FDG uptake from axial (A) and coronal (B) views in RCoA and control subjects. White arrows demonstrate areas of increased aortic 18F-FDG uptake. Global aortic 18F-FDG uptake was significantly increased in RCoA compared with control subjects.

Brili S, Oikonomou E, Antonopoulos AS, Pianou N, Georgakopoulos A, Koutagiar I, Kafouris P, Stroumpouli E, Dounis C, Metaxas M, Spyrou G, Anagnostopoulos CD, Tousoulis D.

18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomographic Imaging Detects Aortic Wall Inflammation in Patients With Repaired Coarctation of Aorta.

Circ Cardiovasc Imaging. 2018 Jan;11(1):e007002. doi: 10.1161/CIRCIMAGING.117.007002.