Επιστημονικό Προσωπικό

Επιλεγμένες Δημοσιεύσεις

Orestis Argyros, Theodoros Karampelas, Xenophon Asvos, Aimilia Varela, Nisar Sayyad, Athanasios Papakyriakou, Constantinos H Davos, Andreas G Tzakos, Demosthenes Fokas, and Constantin Tamvakopoulos. Peptide-drug conjugate GnRH-sunitinib targets angiogenesis selectively at the site of action to inhibit tumor growth. Cancer Res canres.2138.2015; Published OnlineFirst December 8, 2015; doi:10.1158/0008-5472.CAN-15-2138

Stellas D, Szabolcs M, Koul S, Li Z, Polyzos A, Anagnostopoulos C, Cournia Z, Tamvakopoulos C, Klinakis A, Efstratiadis A. (2014) Therapeutic effects of an anti-Myc drug on mouse pancreatic cancer J Natl Cancer Inst. 2014 Oct 11;106(12)

Karampelas T, Argyros O, Sayyad N, Spyridaki K, Pappas C, Morgan K, Kolios G, Millar RP, Liapakis G, Tzakos AG, Fokas D, Tamvakopoulos C.  (2014) GnRH-Gemcitabine Conjugates for the Treatment of Androgen-Independent Prostate Cancer: Pharmacokinetic Enhancements Combined with Targeted Drug Delivery.  Bioconjug Chem. 16;25(4):813-23.

Koltsida O, Karamnov S, Pyrillou K, Vickery T, Chairakaki A-K, Tamvakopoulos C, Sideras P, Serhan CN, Andreakos E (2013) Toll-like receptor 7 stimulates production of specialized pro-resolving lipid mediators and promotes resolution of airway inflammation EMBO Mol Med. ;5(5):762-75

Chatziioannou AN, Siskos AP, Loxas D, Kavatzas, N, Agrogiannis G, Fokas D, Malagari K, Kostomitsopoulos N, Tsigkou O, Tamvakopoulos C (2013) Transarterial Embolization with Sorafenib in animal livers: a pharmacokinetic study. J Vasc Interv Radiol. ;24(11):1657-63

Katsila T, Balafas E, Liapakis G, Limonta P, Montagnani Marelli M, Gkountelias K, Tselios T, Kostomitsopoulos N, Matsoukas J, and Tamvakopoulos C (2011) Evaluation of a stable gonadotropin releasing hormone analogue in mice for the treatment of endocrine disorders and prostate cancer.  J Pharmacol Exp Ther. 336 (3):613-23

Siskos AP, Katsila T, Balafas E, Kostomitsopoulos N, Tamvakopoulos C (2009) Simultaneous Absolute Quantification of the Glucose-Dependent Insulinotropic Polypeptides GIP1-42 and GIP3-42 in Mouse Plasma by LC/ESI-MS/MS: Preclinical Evaluation of DP-IV Inhibitors. J Proteome Res., 8 (7):3487-96.

Garbis SD, Tyritzis SI, Roumeliotis T, Zerefos P, Giannopoulou EG, Vlahou A, Kossida S, Diaz J, Vourekas S, Tamvakopoulos C, Pavlakis K, Sanoudou D, Constantinides CA. (2008) Search for potential markers for prostate cancer diagnosis, prognosis and treatment in clinical tissue specimens using amine-specific isobaric tagging (iTRAQ) with two-dimensional liquid chromatography and tandem mass spectrometry. J Proteome Res. Aug;7(8):3146-58.

Z.D. Sofianos, T. Katsila, N. Kostomitsopoulos, V. Balafas, J. Matsoukas, T. Tselios, and C. Tamvakopoulos (2008) In vivo evaluation and in vitro metabolism of leuprolide in mice—mass spectrometry-based biomarker measurement for efficacy and toxicity J. Mass Spectrom, 43: 1381-1392.

Tamvakopoulos C, Dimas K, Sofianos ZD, Hatziantoniou S, Han Z, Liu ZL, Wyche JH, Pantazis P (2007). Metabolism and anticancer activity of the curcumin analogue, dimethoxycurcumin. Clin Cancer Res. 13(4):1269-77.

Tamvakopoulos C. (2007) Mass spectrometry for the quantification of bioactive peptides in biological fluids. Mass Spectrom Reviews, 26 (3): 389-402.

Van der Ploeg LH, Martin WJ, Howard AD, Nargund RP, Austin CP, Guan X, Drisko J, Cashen D, Sebhat I, Patchett AA, Figueroa DJ, DiLella AG, Connolly BM, Weinberg DH, Tan CP, Palyha OC, Pong SS, MacNeil T, Rosenblum C, Vongs A, Tang R, Yu H, Sailer AW, Fong TM, Huang C, Tota MR, Chang RS, Stearns R, Tamvakopoulos C, Christ G, Drazen DL, Spar BD, Nelson RJ, MacIntyre DE. (2002) A role for the melanocortin 4 receptor in sexual function.  Proc Natl Acad Sci U S A. – 99(17), 11381-11386.

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