Biomedical Research Foundation Academy Of AthensAcademy Of Athens
Scientific Personnel

Emmanouil Emmanouil Athanasiadis, PhD
Staff Research Scientist - Associate Professor Level

e-mail :

Center :

Systems Biology

Brief Bio

Emmanouil (Manos) received his BSc in Biomedical Engineering from the Department of Biomedical Engineering of the Technological Educational Institute of Athens in 2004. He received his MSc and PhD in Medical Physics in 2006 and 2010, respectively, from the University of Patras, both funded by the National State Scholarship Foundation of Greece. He worked as Research Associate in Medical Imaging (Marie Curie) at University Colleague London (UCL) from June to October 2010. From August 2011 to December 2015, he worked as Research Associate in Bioinformatics at Biomedical Research Foundation of the Academy of Athens (BRFAA). From 2010 to 2015 he worked as Adjunct laboratory instructor (lecturer level) at the Department of Biomedical Engineering, Technological Educational Institute of Athens and Lecturer at the Postgraduate Program «Advanced Systems and Methods in Biomedical Engineering», 2014 – 2016. From January 2016 to July 2018 he worked as Research Associate in Bioinformatics at the Department of Haematology at University of Cambridge, also affiliated with the Wellcome Trust Sanger Institute and the Wellcome - MRC Cambridge Stem Cell Institute, while supervising MSc and PhD students from University of Cambridge. From July 2018 until July 2020, He worked as Computational Biologist in Functional Genomics at GSK, while working as Visiting Scientist in OpenTargets and mentoring Research Associates from University of Cambridge. In 2019 he also elected GSK Associate Fellow (top ~5% of people working at GSK’s R&D globally). Since July 2020, He has been elected Group Leader (Staff Research Scientist – Associate Professor level) at BRFAA in the field of “Analysis of Genomic Data” for the needs of Systems Biology Center, also affiliated with OpenTargets working as Visiting Scientist. During his research carrier, he has been awarded with “K. Karatheodoris” scholarship (2018-2010), as well as worked in more than 10 EU funding programs, while his scientific work has been published in more than 30 Journals with Impact Factor (h-index 14). Since 2010, he is also reviewer in more than 10 Scientific journals including Nature, Bioinformatics, Briefings in Bioinformatics, BMC Bioinformatics, Medical Physics, PLOS ONE, etc.

Selected Publications

Analysis of endothelial-to-haematopoietic transition at the single cell level identifies cell cycle regulation as a driver of differentiation, Giovanni C, Athanasiadis E, et al. Genome Biology, 21, 157, 2020, DOI: 10.1101/2020.04.03.023762

ChemBioServer 2.0: An advanced web server for filtering, clustering and networking of chemical compounds facilitating both drug discovery and repurposing, Karatzas E*, Zamora JE*, Athanasiadis E, et al., Bioinformatics, btz97, 2020, DOI:10.1093/bioinformatics/btz976, *Equal First Authors

Single-cell transcriptional analysis reveals ILC-like cells in zebrafish, Hernández P*, Strzelecka P*, Athanasiadis E*, et al. Science immunology, Volume 3, Issue 29, eaau5265, 2018, DOI:10.1126/sciimmunol.aau5265 *Equal First Authors

Single-cell RNA-Sequencing uncovers transcriptional states and fate decisions in haematopoiesis, Athanasiadis E et al. Nature Communications, Volume 8, Issue 1, 2045, 2017, DOI:10.1038/s41467-017-02305-6

D-Map: Random walking on gene network inference maps towards differential avenue discovery, Athanasiadis E, et al. IEEE/ACM Transactions on Computational Biology and Bioinformatics, Volume 14, Issue 2, Pages 484-490, 2017, DOI:10.1109/TCBB.2016.2535267

CD4-transgenic zebrafish reveal tissue-resident Th2- and regulatory T cell-like populations and diverse mononuclear phagocytes, Dee C*, Nagaraju R*, Athanasiadis E, et al. Journal of Immunology, Volume 197, Issue 9, Pages 3520-3530, 2016, DOI: 10.4049/jimmunol.1600959 – *Equal First Authors  **Cover Page

Discovering gene re-ranking efficiency and conserved gene-gene relationships derived from gene co-expression network analysis on breast cancer data, Bourdakou M, Athanasiadis E, et al. Scientific Reports, Volume 19, Issue 6, Pages 20518, 2016, DOI:10.1038/srep20518

Bioinformatics methods in drug repurposing for Alzheimer’s disease, Siavelis J, Bourdakou M, Athanasiadis E, et al. Briefings in Bioinformatics, Volume 17, Issue 2, Pages 322-35, 2016, DOI:10.1093/bib/bbv048

ZoomOut: Analyzing multiple networks as single nodes, Athanasiadis E, et al. IEEE/ACM Transactions on Computational Biology and Bioinformatics, Volume 12, Pages 1213-1216, 2015, DOI: 1109/TCBB.2015.2424411

A database of genetic association studies in melanoma using network-driven data exploration tools. Athanasiadis E, et al. Database, Volume 2014, bau101, 2014, DOI:10.1093/database/bau101

BiDaS: a web-based Monte Carlo BioData Simulator based on sequence/feature characteristics.  Paraskevopoulou M*, Vlachos I*, Athanasiadis E, et al. Nucleic Acids Research, Volume 41, Issue W1, Pages W582-586, 2013, DOI:10.1093%2Fnar%2Fgkt420, *Equal First Authors

ChemBioServer: A web-based pipeline for filtering, clustering and visualization of chemical compounds used in drug discovery, Athanasiadis E, et al. Bioinformatics, Volume 28, Issue 22, Pages 3002-3003, 2012, DOI: 10.1093/bioinformatics/bts551


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