Biomedical Research Foundation Academy Of AthensAcademy Of Athens
Scientific Personnel

George Th. George Th. Tsangaris, PhD
Staff Research Scientist - Professor Level

Telephone : +30 210 6597 075
Fax : +30 210 6597 498
e-mail : gthtsangaris@bioacademy.gr


Center :

Systems Biology

Core Facility Site :

Proteomics


Brief Bio

Dr. George Th. Tsangaris was born in Chios, Greece. He holds a degree in Chemistry at 1983 from the Department of Chemistry, University of Ioannina (Greece) and a PhD in Biochemistry from the same University at 1991. From 1991 to 1993 he was post-doctoral fellow of French Government at INSERM U200 (Paris, France) with research interests in Molecular Biology, Molecular Immunology and Immunotoxicology,  stayed in the same Unit of INSERM as researcher up to 1994. From 1994, he joined the University Research Institute of Genetic and Malignant Diseases (University of Athens, Greece) as principal investigator, responsible for the project “Molecular Study of Childhood Cancer” and as research fellow the Hematology Unit, First Department of Pediatrics, School of Medicine, University of Athens (Greece). In 2002, he joined the Roche Centre for Medical Genomics (Hoffman-La Roche LTD, Basel, Swiss) for sabbatical studies in proteomics. From 2003 he joined the Proteomics Research Unit of the Biomedical Research Foundation of the Academy of Athens as a Research Scientist Level A'. His recent work is contributed to the extensive application of proteomics: a) For the study of human reproduction and specially the identification of biomarkers for the noninvasive prenatal diagnosis of embryonic and pregnancy complications, b) Neuroproteomics with special interest the analysis of normal brain function in animal models (mouse and rat), the brain asymmetry and laterization, and brain tumors with special interest the childhood brain tumors (astrocytoma, medulloblastoma etc.), c) At the development of proteomic-related methodologies including novel approaches for the protein identification with LC-MS/MS, the isolation and identification of naturally-occurring peptides and small proteins in biological materials, d) Food and Nutrition Proteomics with special interest the analysis of origin and the characterization of the food, the analysis of dairy products and the study of pediatric nutrient related diseases, e) The Uniqome: including the development of the bioinformatics approach, the database construction and the biological significance of the unique peptides within the proteome. From his research has published: 110 peer reviewed research papers, 30 review articles, 6 research papers in Greek journals, 4 book chapters, 30 presentations as invited speaker in International and Greek Congresses, and more than 200 abstracts in International and Greek Congresses. Dr. Tsangaris is owner of 7 Greek and 2 European patents, and his research work has many international and Greek awards. He is founded member and President of the Hellenic Proteomics Society, founded member and local representative of the European Preventive, Predictive and Personalized Medicine Association. From 2013-2016 he was member of the Advisory Board of Human Proteome Organisation (HUPO) and from 2016 member at Large of Food and Nutrition Initiative (FaN), founded by HUPO. From 1998 he is member of the Scientific Advisory Board of the International Institute of Anticancer Research, editor of the journal Cancer Genomics and Proteomics and of the Journal of Biomarkers and member of the editorial board of three other international Journals and editor of the special issue of Journal of Proteomics: The key-role of multi-omics in predictive, preventive and personalized medicine as the medicine of the future (vol.188, 2018).

Selected Publications

In Total: 123 papers in international peer-reviewed journals by which 101 original papers, and 22 review papers6 chapters in books, one volume as editor, 11 papers in Greek journals, 28 presentations in International and Greek conferences, 120 abstracts in Intrenanional conferences and 62 abstracts in Greek conferences. 

Total Impact Factor: 327.461. Total citations: 1830 (according to Scopus), h-index: 24 (according to Scopus).

  1. Anagnostopoulos, A.K., Tsangaris, G.T. (2018). Feta cheese proteins: Manifesting the identity of Greece׳s National Treasure. Data in Brief, 19, 2037-2040.
  2. Tsangaris, G.T., Anagnostopoulos, A.K. (2018). Pediatric brain tumors: Update of proteome-based studies. Journal of Proteomics, 188, 41-45.
  3. Kosteria, I., Kanaka-Gantenbein, C., Anagnostopoulos, A.K., Chrousos, G.P., Tsangaris, G.T. (2018). Pediatric endocrine and metabolic diseases and proteomics. Journal of Proteomics, 188, 46-58.
  4. Michailidou, S., Tsangaris, G.T., Fthenakis, G.C., Tzora, A., Skoufos, I., Karkabounas, S.C., Banos, G., Argiriou, A., Arsenos, G. (2018). Genomic diversity and population structure of three autochthonous Greek sheep breeds assessed with genome-wide DNA arrays. Molecular Genetics and Genomics, 293 (3), pp. 753-768.
  5. Tsangaris G.T., Dimas, K., Malamou, A., Katsafadou, A., Papathanasiou, C., Stravopodis, D.J., Vorgias, C.E., Gazouli, M., Anagnostopoulos, A.K. (2017). Molecular proteomic characterization of a pediatric medulloblastoma xenograft. Cancer Genomics and Proteomics, 14(4), 267-275.
  6. Anagnostopoulos, A.K., Stravopodis, D.J., Tsangaris, G.T. (2017). Yield of 6,000 proteins by 1D nLC–MS/MS without pre-fractionation. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 1047, 92-96.
  7. Tsangaris, G.T., Papathanasiou, C., Adamopoulos, P.G., Scorilas, A., Vorgias, C.E., Prodromou, N., Stathopoulou, F.T., Stravopodis, D.J., Anagnostopoulos, A.K. (2017).  Pediatric ependymoma: A proteomics perspective. Cancer Genomics and Proteomics, 14 (2), 127-136.
  8. Anagnostopoulos, A.K., Katsafadou, A.I., Pierros, V., Kontopodis, E., Fthenakis, G.C., Arsenos, G., Karkabounas, S.C., Tzora, A., Skoufos, I., Tsangaris, G.T. (2016). Milk of Greek sheep and goat breeds; characterization by means of proteomics. Journal of Proteomics, 147, 76-84.
  9. Anagnostopoulos, A.K., Papathanassiou, C., Karamolegou, K., Anastasiadou, E., Dimas, K.S., Kontos, H., Koutsopoulos, A., Prodromou, N., Tzortzatou-Stathopoulou, F., Tsangaris, G.T. (2015). Proteomic studies of pediatric medulloblastoma tumors with 17p deletion. Journal of Proteome Research, 14 (2), 1076-1088.
  10. Balfoussia, E., Skenderi, K., Tsironi, M., Anagnostopoulos, A.K., Parthimos, N., Vougas, K., Papassotiriou, I., Tsangaris, G.T., Chrousos, G.P. (2014). A proteomic study of plasma protein changes under extreme physical stress. Journal of Proteomics, 98, 1-14.
  11. Calciolari, E., Mardas, N., Dereka, X., Anagnostopoulos, A.K., Tsangaris, G.T., Donos, N. (2018). Protein expression during early stages of bone regeneration under hydrophobic and hydrophilic titanium domes. A pilot study. Journal of Periodontal Research, 53 (2), 174-187.
  12. Vaiopoulou, A., Gazouli, M., Papadopoulou, A., Anagnostopoulos, A.K., Karamanolis, G., Theodoropoulos, G.E., M'koma, A., Tsangaris, G.T. (2015). Serum protein profiling of adults and children with Crohn disease. Journal of Pediatric Gastroenterology and Nutrition, 60 (1), 42-47.

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