Biomedical Research Foundation Academy Of AthensAcademy Of Athens
Scientific Personnel

Ioannis Ioannis Michalopoulos, PhD
Staff Research Scientist - Associate Professor Level

Telephone : +30 210 6597 127
Fax : +30 210 6597 545
e-mail :

Center :

Systems Biology

Lab Site :

Michalopoulos Lab

Brief Bio

Ioannis Michalopoulos received his BSc in Biology from the University of Athens and his PhD in Molecular Biology from the University of St Andrews. Soon after the publication of the first draft of the human genome, he moved to Bioinformatics, doing post-doctoral research in the University of Leeds (2001-2005) and in the Biomedical Research Centre of the Academy of Athens (2006-2008). Since 2008, Ioannis Michalopoulos is working as Staff Research Scientist – Associate Professor Level in the Division of Cryobiology of Stem Cells of the Centre of Immunology and Transplantation of the Biomedical Research Foundation, Academy of Athens. He is in charge of the design and maintenance of various biobank web sites (Hellenic Cord Blood Bank, Biobanking and Biomolecular Resources Research Infrastructure (BBMRI-GR), Hellenic Databank for Parkinson Disease, etc). His research activities include many collaboration projects with experimental researchers and computer scientists in the field of Genomics, Transcriptomics, Epigenomics, Proteomics, etc. Ioannis Michalopoulos is a founding member of the Hellenic Society of Computation Biology and Bioinformatics. He belongs to the Teaching Staff of the MSc Programme in Bioinformatics of the Faculty of Biology of the University of Athens, teaching parts of “Molecular Recognition” and “Microarrays” courses. He is a reviewer of Nucleic Acid Research, Bioinformatics and PLoS One.

Selected Publications

Giannopoulos, N.G., Michalopoulos, I., Papandreou, N.C., Malatras, A., Iconomidou, V.A., and Hamodrakas, S.J. (2012) LepChorionDB, a database of Lepidopteran chorion proteins and a set of tools useful for the identification of chorion proteins in Lepidopteran proteomes. Insect Biochem Mol Biol, doi:10.1016/j.ibmb.2012.12.001

Logotheti, S., Papaevangeliou, D., Michalopoulos, I., Sideridou, M., Tsimaratou, K., Christodoulou, I., Pyrillou, K., Gorgoulis, V., Vlahopoulos, S., and Zoumpourlis, V. (2012). Progression of mouse skin carcinogenesis is associated with increased ERα levels and is repressed by a dominant negative form of ERα. PLoS One 7, e41957.

Michalopoulos, I., Pavlopoulos, G.A., Malatras, A., Karelas, A., Kostadima, M.A., Schneider, R., and Kossida, S. (2012). Human gene correlation analysis (HGCA): A tool for the identification of transcriptionally coexpressed genes. BMC Res Notes 5, 265.

Pavlopoulou, A., and Michalopoulos, I. (2011). State-of-the-art bioinformatics protein structure prediction tools (Review). Int J Mol Med 28, 295-310.

Pavlopoulou, A., Pampalakis, G., Michalopoulos, I., and Sotiropoulou, G. (2010). Evolutionary history of tissue kallikreins. PLoS One 5, e13781.

Logotheti, S., Michalopoulos, I., Sideridou, M., Daskalos, A., Kossida, S., Spandidos, D.A., Field, J.K., Vojtesek, B., Liloglou, T., Gorgoulis, V., Zoumpourlis, V. (2010). Sp1 binds to the external promoter of the p73 gene and induces the expression of TAp73γ in lung cancer. The FEBS J 277,  3014-3027.

Roubelakis, M.G., Zotos, P., Papachristoudis, G., Michalopoulos, I., Pappa, K.I., Anagnou, N.P., and Kossida, S. (2009). Human microRNA target analysis and gene ontology clustering by GOmir, a novel stand-alone application. BMC Bioinformatics 10 Suppl 6, S20.

Manfield, I.W., Jen, C.H., Pinney, J.W., Michalopoulos, I., Bradford, J.R., Gilmartin, P.M., and Westhead, D.R. (2006). Arabidopsis Co-expression Tool (ACT): web server tools for microarray-based gene expression analysis. Nucleic Acids Res 34, W504-509.

Jen, C.H., Manfield, I.W., Michalopoulos, I., Pinney, J.W., Willats, W.G., Gilmartin, P.M., and Westhead, D.R. (2006). The Arabidopsis co-expression tool (ACT): a WWW-based tool and database for microarray-based gene expression analysis. Plant J 46, 336-348.

Jen, C.H., Michalopoulos, I., Westhead, D.R., and Meyer, P. (2005). Natural antisense transcripts with coding capacity in Arabidopsis may have a regulatory role that is not linked to double-stranded RNA degradation. Genome Biol 6, R51.

Torrance, G.M., Gilbert, D.R., Michalopoulos, I., and Westhead, D.W. (2005). Protein structure topological comparison, discovery and matching service. Bioinformatics 21, 2537-2538.

Michalopoulos, I., Torrance, G.M., Gilbert, D.R., and Westhead, D.R. (2004). TOPS: an enhanced database of protein structural topology. Nucleic Acids Res 32, D251-254.


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