Fields of Research

Head: Prof. George P. Chrousos, MD, MACP, MACE

The Division of Endocrinology and Metabolism studies the physiology and pathophysiology of the hypothalamic-pituitary-adrenal (HPA) and gonadal (HPG) axes and the autonomic nervous system, as they relate to each other, and as they influence growth, development, metabolic and immune functions. Both the developmental and static functions of these neurohormonal systems are studied at the integrated level in health and disease. Also, the cellular/subcellular and genomic actions of the key effector molecules of these systems, including corticotropin-releasing hormone (CRH), arginine-vasopressin (AVP), corticotropin (ACTH), glucocorticoids, mineralocorticoids, gonadotropins, estrogens, progestins, androgens and catecholamines, are studied as they relate to normal physiology and disease-related pathophysiology.

Research projects of the Division of Endocrinology and Metabolism focus on the delineation of the molecular mechanisms of glucocorticoid signaling in health and disease.