Dimitrios Boumpas and colleagues recently published a study in Frontiers in Immunology

In this work, we used RNA-sequencing of whole-blood samples and subsequent bioinformatic analysis to explore the non-coding transcriptome of Lupus Nephritis patients and highlight long non-coding RNAs that could be promising biomarkers of disease activity. This could eventually be translated into a blood-based "liquid biopsy" that will replace the current approach which is invasive and risky kidney biopsies.

pubmed

A network-based approach reveals long non-coding RNAs associated with disease activity in lupus nephritis: key pathways for flare and potential biomarkers to be used as liquid biopsies.
Sentis G, Loukogiannaki C, Malissovas N, Nikolopoulos D, Manolakou T, Flouda S, Grigoriou M, Banos A, Boumpas DT, Filia A. Front Immunol. 2023 Jul 5;14:1203848. doi: 10.3389/fimmu.2023.1203848. eCollection 2023.PMID: 37475860