Biomedical Research Foundation Academy Of AthensAcademy Of Athens
2018 Publications

BRFAA - Publications - 2019
BRFAA - Publications - 2018
BRFAA - Publications - 2017
BRFAA - Publications - 2016
BRFAA - Publications - 2015
BRFAA - Publications - 2014
BRFAA - Publications - 2013
BRFAA - Publications - 2012
BRFAA - Publications - 2011
BRFAA - Publications - 2010
BRFAA - Publications - 2009
BRFAA - Publications - 2008
BRFAA - Publications - 2007
BRFAA - Publications - 2006
BRFAA - Publications - 2005
BRFAA - Publications - 2004
BRFAA - Publications - 2003

 


Kyrochristos ID, Ziogas DE, Antoniou P, Mitsis M, Lykoudis EG, Roukos DH. Breakthrough cancer genome analysis in time and space: novel oncotargets and early drug development. Pharmacogenomics. 2018 Nov;19(17):1303-1310. doi: 10.2217/pgs-2018-0141.

Nakos I, Kadoglou NPE, Gkeka P, Tzallas AT, Giannakeas N, Tsalikakis DG, Katsimpoulas M, Mantziaras G, Kostomitsopoulos N, Liapis CD, Kakisis J. Exercise Training Attenuates the Development of Cardiac Autonomic Dysfunction in Diabetic Rats. In Vivo. 2018 Nov-Dec;32(6):1433-1441. doi: 10.21873/invivo.11396.

Salta S, Papageorgiou L, Larsen AK, Van Dreden P, Soulier C, Cokkinos DV, Elalamy I, Gerotziafas GT. Comparison of antithrombin-dependent and direct inhibitors of factor Xa or thrombin on the kinetics and qualitative characteristics of blood clots. Res Pract Thromb Haemost. 2018 Jul 17;2(4):696-707. doi: 10.1002/rth2.12120.

Podewitz M, Wang Y, Gkeka P, von Grafenstein S, Liedl KR, Cournia Z. Phase Diagram of a Stratum Corneum Lipid Mixture. J Phys Chem B. 2018 Nov 21;122(46):10505-10521. doi: 10.1021/acs.jpcb.8b07200

Gkirtzimanaki K, Kabrani E, Nikoleri D, Polyzos A, Blanas A, Sidiropoulos P, Makrigiannakis A, Bertsias G, Boumpas DT, Verginis P. IFNα Impairs Autophagic Degradation of mtDNA Promoting Autoreactivity of SLE Monocytes in a STING-Dependent Fashion. Cell Rep. 2018 Oct 23;25(4):921-933.e5. doi: 10.1016/j.celrep.2018.09.001.

Kosmidis S, Polyzos A, Harvey L, Youssef M, Denny CA, Dranovsky A, Kandel ER. RbAp48 Protein Is a Critical Component of GPR158/OCN Signaling and Ameliorates Age-Related Memory Loss. Cell Rep. 2018 Oct 23;25(4):959-973.e6. doi: 10.1016/j.celrep.2018.09.077.

Ziogas DE, Kyrochristos ID, Lykoudis EG, Roukos DH. Early solid tumor diagnosis through next-generation sequencing of cell-free DNA. Biomark Med. 2018 Nov;12(11):1197-1201. doi: 10.2217/bmm-2018-0269

Velentzas AD, Velentzas PD, Katarachia SA, Anagnostopoulos AK, Sagioglou NE, Thanou EV, Tsioka MM, Mpakou VE, Kollia Z, Gavriil VE, Papassideri IS, Tsangaris GT, Cefalas AC, Sarantopoulou E, Stravopodis DJ. The indispensable contribution of s38 protein to ovarian-eggshell morphogenesis in Drosophila melanogaster. Sci Rep. 2018 Oct 31;8(1):16103. doi: 10.1038/s41598-018-34532-2.

Kyrochristos ID, Ziogas DE, Roukos DH. Precision in personalized prediction-based medicine. Per Med. 2018 Nov;15(6):467-470. doi: 10.2217/pme-2018-0079.

Mallis P, Boulari D, Michalopoulos E, Dinou A, Spyropoulou-Vlachou M, Stavropoulos-Giokas C. Evaluation of HLA-G Expression in Multipotent Mesenchymal Stromal Cells Derived from Vitrified Wharton's Jelly Tissue. Bioengineering (Basel). 2018 Nov 1;5(4). pii: E95. doi: 10.3390/bioengineering5040095

Andreakos E, Zanoni I, Galani IE. Lambda interferons come to light: dual function cytokines mediating antiviral immunity and damage control. Curr Opin Immunol. 2018 Nov 3;56:67-75. doi: 10.1016/j.coi.2018.10.007

Mavrogenis AF, Saranteas T, Markatos K, Kotsiou A, Tesseromatis C. Pharmacies for pain and trauma in ancient Greece. Int Orthop. 2018 Nov 9. doi: 10.1007/s00264-018-4219-x.

Kyrochristos ID, Ziogas DE, Roukos DH. Dynamic genome and transcriptional network-based biomarkers and drugs: precision in breast cancer therapy. Med Res Rev. 2018 Nov 11. doi: 10.1002/med.21549

Vaikath NN, Erskine D, Morris CM, Majbour NK, Vekrellis K, Li JY, El-Agnaf OMA. Heterogeneity in α-synuclein subtypes and their expression in cortical brain tissue lysates from Lewy body diseases and Alzheimer's disease. Neuropathol Appl Neurobiol. 2018 Nov 13. doi: 10.1111/nan.12531.

Gkioka V, Tsirigotis P, Sarris M, Soulis S, Apostolou A, Noutsias M, Dimitriadis G, Kostakis A, Boletis I, Karabinis A. Biovigilance for the Quality and Safety of Medical Products of Human Origin. J Clin Med Res. 2018 Dec;10(12):857-867. doi: 10.14740/jocmr3549w.

Lallo A, Gulati S, Schenk MW, Khandelwal G, Berglund UW, Pateras IS, Chester CPE, Pham TM, Kalderen C, Frese KK, Gorgoulis VG, Miller C, Blackhall F, Helleday T, Dive C. Ex vivo culture of cells derived from circulating tumour cell xenograft to support small cell lung cancer research and experimental therapeutics. Br J Pharmacol. 2019 Feb;176(3):436-450. doi: 10.1111/bph.14542.

Furth N, Pateras IS, Rotkopf R, Vlachou V, Rivkin I, Schmitt I, Bakaev D, Gershoni A, Ainbinder E, Leshkowitz D, Johnson RL, Gorgoulis VG, Oren M, Aylon Y. LATS1 and LATS2 suppress breast cancer progression by maintaining cell identity and metabolic state. Life Sci Alliance. 2018 Oct 30;1(5):e201800171. doi: 10.26508/lsa.201800171.

Smart NA, Taylor R, Walker S, Warren F, Ciani O, Davos CH, Piepoli M. Exercise training for chronic heart failure (ExTraMATCH II): Why all data are not equal. Eur J Prev Cardiol. 2018 Nov 22:2047487318815314. doi: 10.1177/2047487318815314.

Gontika I, Katsimpoulas M, Antoniou E, Kostakis A, Stavropoulos-Giokas C, Michalopoulos E. Decellularized Human Umbilical Artery Used as Nerve Conduit. Bioengineering (Basel). 2018 Nov 21;5(4). pii: E100. doi: 10.3390/bioengineering5040100

Cooks T, Theodorou SD, Paparouna E, Rizou SV, Myrianthopoulos V, Gorgoulis VG, Pateras IS. Immunohisto(cyto)chemistry: an old time classic tool driving modern oncological therapies. Histol Histopathol. 2018 Nov 27:18069. doi: 10.14670/HH-18-069

Ansar M, Paracha SA, Serretti A, Sarwar MT, Khan J, Ranza E, Falconnet E, Iwaszkiewicz J, Shah SF, Qaisar AA, Santoni FA, Zoete V, Megarbane A, Ahmed J, Colombo R, Makrythanasis P, Antonarakis SE. Biallelic variants in FBXL3 cause intellectual disability, delayed motor development and short stature. Hum Mol Genet. 2018 Nov 26. doi: 10.1093/hmg/ddy406.

Karamatsoukis SL, Trigka EA, Stasinopoulou M, Stavridou A, Zacharioudaki A, Tsarea K, Karamperi M, Pittaras T, Papadopoulos O, Patsouris E, Nikiteas N, Zografos GC, Papalois AE. Beneficial Effect of U-74389 G and Sildenafil in An Experimental Model of Flap Ischemia/Reperfusion Injury in Swine. Histological and Biochemical Evaluation of the Model. J Invest Surg. 2018 Nov 30:1-13. doi: 10.1080/08941939.2018.1524527.

Vlahou A. Implementation of Clinical Proteomics: A Step Closer to Personalized Medicine? Proteomics Clin Appl. 2018 Dec 6:e1800088. doi: 10.1002/prca.201800088

Lobachevsky PN, Ventura J, Giannakandropoulou L, Forrester H, Palazzolo JS, Haynes NM, Stevenson AW, Hall CJ, Mason J, Pollakis G, Pateras IS, Gorgoulis V, Terzoudi GI, Hamilton JA, Sprung CN, Georgakilas AG, Martin OA. A Functional Immune System Is Required for the Systemic Genotoxic Effects of Localized Irradiation. Int J Radiat Oncol Biol Phys. 2018 Dec 6. pii: S0360-3016(18)34068-9. doi: 10.1016/j.ijrobp.2018.11.066

Rigas P, Sigalas C, Nikita M, Kaplanian A, Armaos K, Leontiadis LJ, Zlatanos C, Kapogiannatou A, Peta C, Katri A, Skaliora I. Long-Term Effects of Early Life Seizures on Endogenous Local Network Activity of the Mouse Neocortex. Front Synaptic Neurosci. 2018 Nov 27;10:43. doi: 10.3389/fnsyn.2018.00043.

Johnson SR, Khanna D, Daikh D, Cervera R, Costedoat-Chalumeau N, Gladman DD, Hahn BH, Hiepe F, Sánchez-Guerrero J, Massarotti E, Boumpas DT, Costenbader KH, Jayne D, Dörner T, Kamen DL, Mosca M, Ramsey-Goldman R, Smolen JS, Wofsy D, Aringer M. Use of Consensus Methodology to Determine Candidate Items for Systemic Lupus Erythematosus Classification Criteria. J Rheumatol. 2018 Dec 15. pii: jrheum.180478. doi: 10.3899/jrheum.180478.

Markatos K, Androutsos G, Karamanou M, Kaseta M, Korres D, Mavrogenis A. Spine deformities and trauma in Avicenna's Canon of Medicine. Int Orthop. 2018 Dec 15. doi: 10.1007/s00264-018-4278-z.

Aydindogan E, Penque D, Zoidakis J. Systematic review on recent potential biomarkers of chronic obstructive pulmonary disease. Expert Rev Mol Diagn. 2018 Dec 18:1-9. doi: 10.1080/14737159.2018.1559054.

Chase A, Pellagatti A, Singh S, Score J, Tapper WJ, Lin F, Hoade Y, Bryant C, Trim N, Yip BH, Zoi K, Rasi C, Forsberg LA, Dumanski JP, Boultwood J, Cross NCP. PRR14L mutations are associated with chromosome 22 acquired uniparental disomy, age-related clonal hematopoiesis and myeloid neoplasia. Leukemia. 2018 Dec 20. doi: 10.1038/s41375-018-0340-5.

Christodoulou E, Grafakou ME, Skaltsa E, Kadoglou N, Kostomitsopoulos N, Valsami G. Preparation, chemical characterization and determination of crocetin's pharmacokinetics after oral and intravenous administration of saffron (Crocus sativus L.) aqueous extract to C57/BL6J mice. J Pharm Pharmacol. 2018 Dec 21. doi: 10.1111/jphp.13055.

Katsimpoulas M, Morticelli L, Gontika I, Kouvaka A, Mallis P, Dipresa D, Böer U, Soudah B, Haverich A, Michalopoulos E, Korossis SA. Biocompatibility and Immunogenicity of Decellularised Allogeneic Aorta in the Orthotopic Rat Model. Tissue Eng Part A. 2018 Dec 22. doi: 10.1089/ten.TEA.2018.0037.

Mallis P, Chachlaki P, Katsimpoulas M, Stavropoulos-Giokas C, Michalopoulos E. Optimization of Decellularization Procedure in Rat Esophagus for Possible Development of a Tissue Engineered Construct. Bioengineering (Basel). 2018 Dec 24;6(1). pii: E3. doi: 10.3390/bioengineering6010003.

Markatos K, Chytas D, Tsakotos G, Karamanou M, Piagkou M, Johnson E. Vesalius criticism on Galen's musculoskeletal anatomy. Acta Chir Belg. 2018 Dec 31:1-5. doi: 10.1080/00015458.2018.1554365.

Christaki EE, Politou M, Antonelou M, Athanasopoulos A, Simantirakis E, Seghatchian J, Vassilopoulos G. Ex vivo generation of transfusable red blood cells from various stem cell sources: A concise revisit of where we are now. Transfus Apher Sci. 2018 Dec 31. pii: S1473-0502(18)30485-3. doi: 10.1016/j.transci.2018.12.015.

Kalapanida D, Zagouri F, Gazouli M, Zografos E, Dimitrakakis C, Marinopoulos S, Giannos A, Sergentanis TN, Kastritis E, Terpos E, Dimopoulos MA. Evaluation of pre-mir-34a rs72631823 single nucleotide polymorphism in triple negative breast cancer: A case-control study. Oncotarget. 2018 Dec 11;9(97):36906-36913. doi: 10.18632/oncotarget.26385.

Roumelioti FM, Louizou E, Karras S, Neroutsou R, Velissariou V, Gagos S. Unbalanced X;9 translocation in an infertile male with de novo duplication Xp22.31p22.33. J Assist Reprod Genet. 2019 Jan 24. doi: 10.1007/s10815-019-01405-0.

Giannios I, Serafimidis I, Anastasiou V, Pezzolla D, Lesche M, Andree C, Bickle M, Gavalas A. Protein Methyltransferase Inhibition Decreases Endocrine Specification Through the Upregulation of Aldh1b1 Expression. Stem Cells. 2019 Jan 25. doi: 10.1002/stem.2979.

Aspridou Z, Balomenos A, Tsakanikas P, Manolakos E, Koutsoumanis K. Heterogeneity of single cell inactivation: Assessment of the individual cell time to death and implications in population behavior. Food Microbiol. 2019 Jun;80:85-92. doi: 10.1016/j.fm.2018.12.011.

Kafouris PP, Koutagiar IP, Georgakopoulos AT, Pianou NK, Metaxas MG, Spyrou GM, Anagnostopoulos CD. Adjustment of vascular 2-deoxy-2-[18F]fluoro-D-glucose uptake values over time through a modeling approach. Int J Cardiovasc Imaging. 2019 Jan 31. doi: 10.1007/s10554-018-01514-4.

Critselis E. Impact of the General Data Protection Regulation on Clinical Proteomics Research. Proteomics Clin Appl. 2019 Feb 1:e1800199. doi: 10.1002/prca.201800199.

Katsantoni E. Omics Studies in Hemoglobinopathies. Mol Diagn Ther. 2019 Feb 2. doi: 10.1007/s40291-019-00386-1.

Pappas AG, Magkouta S, Pateras IS, Skianis I, Moschos C, Vazakidou ME, Psarra K, Gorgoulis VG, Kalomenidis I. Versican modulates tumor-associated macrophage properties to stimulate mesothelioma growth. Oncoimmunology. 2018 Nov 2;8(2):e1537427. doi: 10.1080/2162402X.2018.1537427.

Bougea A, Stefanis L, Paraskevas GP, Emmanouilidou E, Vekrelis K, Kapaki E. Plasma alpha-synuclein levels in patients with Parkinson's disease: a systematic review and meta-analysis. Neurol Sci. 2019 Feb 4. doi: 10.1007/s10072-019-03738-1.

Lygirou V, Latosinska A, Makridakis M, Mullen W, Delles C, Schanstra JP, Zoidakis J, Pieske B, Mischak H, Vlahou A. Plasma proteomic analysis reveals altered protein abundances in cardiovascular disease. J Transl Med. 2018 Apr 17;16(1):104. doi: 10.1186/s12967-018-1476-9.PMID: 29665821

Damalas DE, Bletsou AA, Agalou A, Beis D, Thomaidis NS. Assessment of the Acute Toxicity, Uptake and Biotransformation Potential of Benzotriazoles in Zebrafish ( Danio rerio) Larvae Combining HILIC- with RPLC-HRMS for High-Throughput Identification. Environ Sci Technol. 2018 May 15;52(10):6023-6031. doi: 10.1021/acs.est.8b01327. Epub 2018 Apr 30.PMID: 29683664

Luong TTD, Schelski N, Boehme B, Makridakis M, Vlahou A, Lang F, Pieske B, Alesutan I, Voelkl J. Fibulin-3 Attenuates Phosphate-Induced Vascular Smooth Muscle Cell Calcification by Inhibition of Oxidative Stress. Cell Physiol Biochem. 2018;46(4):1305-1316. doi: 10.1159/000489144. Epub 2018 Apr 18.PMID: 29689558

Pyrillou K, Chairakaki AD, Tamvakopoulos C, Andreakos E. Dexamethasone induces ω3-derived immunoresolvents driving resolution of allergic airway inflammation. J Allergy Clin Immunol. 2018 Apr 24. pii: S0091-6749(18)30612-2. doi: 10.1016/j.jaci.2018.04.004. [Epub ahead of print] No abstract available. PMID: 29698628

Tsoucalas G, Markatos K, Karamanou M. The Hippocratic Method of Surgical Cauterization for the Tumescence Spleen in the Rare "Spetses Syndrome". Surg Innov. 2018 Apr 1:1553350618771800. doi: 10.1177/1553350618771800. [Epub ahead of print]PMID: 29701136

Moschos MM, Moustafa GA, Lavaris A, Damaskos C, Laios K, Karathanou E, Ladas DS, Asproudis I, Garmpis N, Kalogeropoulos C. Depression in Choroidal Melanoma Patients Treated with Proton Beam Radiotherapy.  Anticancer Res. 2018 May;38(5):3055-3061.PMID: 29715140

Markatos K, Androutsos G, Karamanou M, Tzagkarakis G, Kaseta M, Mavrogenis A.  Jean-Louis Petit(1674-1750): a pioneer anatomist and surgeon and his contribution to orthopaedic surgery and trauma surgery. Int Orthop. 2018 May 11. doi: 10.1007/s00264-018-3978-8. [Epub ahead of print] Review.PMID: 29752505

Pappa E, Vastardis H, Mermelekas G, Gerasimidi-Vazeou A, Zoidakis J, Vougas K. Saliva ProteomicsAnalysis Offers Insights on Type 1 Diabetes Pathology in a PediatricPopulation. Front Physiol. 2018 Apr 26;9:444. doi: 10.3389/fphys.2018.00444. eCollection 2018.PMID: 29755368

Gorgoulis VG, Pefani DE, Pateras IS, Trougakos IP. Integrating the DNA damage and protein stress responses during cancer development and treatment. J Pathol. 2018 May 13. doi: 10.1002/path.5097. [Epub ahead of print] Review.PMID: 29756349

Brusa R, Magri F, Papadimitriou D, Govoni A, Del Bo R, Ciscato P, Savarese M, Cinnante C, Walter MC, Abicht A, Bulst S, Corti S, Moggio M, Bresolin N, Nigro V, Comi GP. A new case of limb girdle muscular dystrophy 2G in a Greek patient, founder effect and review of the literature. Neuromuscul Disord. 2018 Apr 13. pii: S0960-8966(17)31376-7. doi: 10.1016/j.nmd.2018.04.006.PMID: 29759638

Liu GS, Gardner G, Adly G, Jiang M, Cai WF, Lam CK, Alogaili F, Robbins N, Rubinstein J, Kranias EG. A novel human S10F-Hsp20 mutation induces lethal peripartum cardiomyopathy. J Cell Mol Med. 2018 May 15. doi:
10.1111/jcmm.13665. [Epub ahead of print]PMID: 29761889

Theodoridis PG, Davos CH, Dodos I, Iatrou N, Potouridis A, Pappas GM, Staramos D, Antoniadis P, Argitis V, Dervisis K. Thrombolysis in Acute Lower Limb Ischemia. Review of the Current Literature. Ann Vasc Surg. 2018 May 14. pii: S0890-5096(18)30309-1. doi: 10.1016/j.avsg.2018.02.030. [Epub ahead of print] Review.PMID: 29772326

Magkouta S, Pappas A, Pateras IS, Kollintza A, Moschos C, Vazakidou ME, Karavana V, Gorgoulis VG, Kalomenidis I. Targeting Tie-2/angiopoietin axis in experimental mesothelioma confers differential responses and raises predictive implications. Oncotarget. 2018 Apr 24;9(31):21783-21796. doi: 10.18632/oncotarget.25004. eCollection 2018 Apr 24.PMID: 29774102

Stefa A, Lamprokostopoulou A, Briana DD, Kontogeorgou A, Papageorgiou I, Malamitsi-Puchner A, Tsitsilonis O, Gagos S, Charmandari E. The effect of intrauterine growth on leukocyte telomere length at birth. J Matern Fetal Neonatal Med. 2018 May 20:1-161. doi: 10.1080/14767058.2018.1479392. [Epub ahead of print] PMID: 29779414

Markatos K, Karaoglanis G, Damaskos C, Garmpis N, Tsourouflis G, Laios K, Tsoucalas G. Karl Ludloff (1864-1945): An Inventive Orthopedic Surgeon, His Work and His Surgical Technique for the Correction of Hallux
Valgus.
Surg Innov. 2018 May 1:1553350618775506. doi: 10.1177/1553350618775506. [Epub ahead of print]PMID: 29781363

Papageorgiou L, Eleni P, Raftopoulou S, Mantaiou M, Megalooikonomou V, Vlachakis D. Genomic big data hitting the storage bottleneck. EMBnet J. 2018;24. pii: e910. Epub 2018 Apr 19. PMID: 29782620

Frantzi M, Latosisnka A, Kontostathi G, Mischak H. Clinical proteomics: closing the gap from discovery to implementation. Proteomics. 2018 May 21: e1700463. doi: 10.1002/pmic.201700463. [Epub ahead of print] PMID: 29785737

Fragopoulou AF, Polyzos A, Papadopoulou MD, Sansone A, Manta AK, Balafas E, Kostomitsopoulos N, Skouroliakou A, Chatgilialoglu C, Georgakilas A, Stravopodis DJ, Ferreri C, Thanos D, Margaritis LH. Hippocampal lipidome and transcriptome profile alterations triggered by acute exposure of mice to GSM 1800 MHz mobile phone radiation: An exploratory study. Brain Behav. 2018 May 22:e01001. doi: 10.1002/brb3.1001. [Epub ahead of print] PMID: 29786969

Pefani DE, Tognoli ML, Pirincci Ercan D, Gorgoulis V, O'Neill E. MST2 kinase suppresses rDNA transcription in response to DNA damage by phosphorylating nucleolar histone H2B. EMBO J. 2018 May 22. pii: e98760. doi: 10.15252/embj.201798760. [Epub ahead of print]PMID: 29789391 [PubMed - as supplied by publisher]   Free Article   Similar articles 

Markatos K, Mavrogenis AF, Karamanou M, Androutsos G. Pycnodysostosis: the disease of Henri de Toulouse-Lautrec. Eur J Orthop Surg Traumatol. 2018 May 24. doi: 10.1007/s00590-018-2233-8. [Epub ahead of print] Review.PMID: 29797092

Dimitriadi A, Beis D, Arvanitidis C, Adriaens D, Koumoundouros G. Developmental temperature has persistent, sexually dimorphic effects on
zebrafish cardiac anatomy.
Sci Rep. 2018 May 25;8(1):8125. doi: 10.1038/s41598-018-25991-8.PMID: 29802254

Kyrochristos ID, Peristeri DV, Ziogas DE, Lykoudis EG, Roukos DH. Precise predictive and therapeutic strategy for breast cancer. Future Oncol. 2018 May 30. doi: 10.2217/fon-2018-0277. [Epub ahead of print] No abstract available. PMID: 29846090

Aravanis CV, Kapelouzou A, Vagios S, Tsilimigras DI, Katsimpoulas M, Moris D, Demesticha TD, Schizas D, Kostakis A, Machairas A, Liakakos T. Toll-Like Receptors -2, -3, -4 and -7 Expression Patterns in the Liver of a CLP-Induced Sepsis Mouse Model. J Invest Surg. 2018 May 30:1-9. doi: 10.1080/08941939.2018.1476630.

Papadopoulos VE, Nikolopoulou G, Antoniadou I, Karachaliou A, Arianoglou G, Emmanouilidou E, Sardi SP, Stefanis L6, Vekrellis K. Modulation of β-Glucocerebrosidase Increases α-Synuclein secretion and Exosome release in Mouse Models of Parkinson's Disease. Hum Mol Genet. 2018 Mar 14. doi: 10.1093/hmg/ddy075. [Epub ahead of print]

Liu Z, Pouli D, Alonzo CA, Varone A, Karaliota S, Quinn KP, Münger K, Karalis KP, Georgakoudi I. Mapping metabolic changes by noninvasive, multiparametric, high-resolution imaging using endogenous contrast. Sci Adv. 2018 Mar 7;4(3):eaap9302. doi: 10.1126/sciadv.aap9302. eCollection 2018 Mar.

Kapodistria K, Tsilibary EP, Kotsopoulou E, Moustardas P, Kitsiou P. Liraglutide, a human glucagon-like peptide-1 analogue, stimulates AKT-dependent survival signalling and inhibits pancreatic β-cell apoptosis. J Cell Mol Med. 2018 Mar 10. doi: 10.1111/jcmm.13259. [Epub ahead of print]

Semitekolou M, Xanthou G. ALCAM: A Novel Regulator of Allergic Inflammation in the Airways. Am J Respir Crit Care Med. 2018 Mar 9. doi: 10.1164/rccm.201801-0196ED. [Epub ahead of print] No abstract available.

Kalogeropulou AF, Zhao J, Bolliger MF, Memou A, Narasimha S, Molitor TP, Wilson WH, Rideout HJ, Nichols RJ. p62/SQSTM1 is a novel Leucine Rich Repeat Kinase 2(LRRK2) substrate that enhances neuronal toxicity. Biochem J. 2018 Mar 8. pii: BCJ20170699. doi: 10.1042/BCJ20170699. [Epub ahead of print]

Chaniotakis I, Antoniou E, Kostomitsopoulos N, Karapsias S, Mirilas P, Salakos C. Stress response to ovariohysterectomy in rabbits: role of anaesthesia and surgery. J Obstet Gynaecol. 2018 Mar 8:1-5. doi: 10.1080/01443615.2017.1400523. [Epub ahead of print]

Kraniotou C, Karadima V, Bellos G, Tsangaris GT. Predictive biomarkers for type 2 of diabetes mellitus: bridging the gap between systems research and personalized medicine. J Proteomics. 2018 Mar 5. pii: S1874-3919(18)30099-X. doi: 10.1016/j.jprot.2018.03.004. [Epub ahead of print]

Moysidou M, Karaliota S, Kodela E, Salagianni M, Koutmani Y, Katsouda A, Kodella K, Tsakanikas P, Ourailidou S, Andreakos E, Kostomitsopoulos N, Skokos D, Chatzigeorgiou A, Chung KJ, Bornstein S, Sleeman MW, Chavakis T, Karalis KP. CD8+ T cells in beige adipogenesis and energy homeostasis. JCI Insight. 2018 Mar 8;3(5). pii: 95456. doi: 10.1172/jci.insight.95456. [Epub ahead of print]

Reebye V, Huang KW, Lin V, Jarvis S, Cutilas P, Dorman S, Ciriello S, Andrikakou P, Voutila J, Saetrom P, Mintz PJ, Reccia I, Rossi JJ, Huber H, Habib R, Kostomitsopoulos N, Blakey DC, Habib NA. Gene activation of CEBPA using saRNA: preclinical studies of the first in human saRNA drug candidate for liver cancer. Oncogene. 2018 Mar 7. doi: 10.1038/s41388-018-0126-2. [Epub ahead of print]

Christou I, Mallis P, Michalopoulos E, Chatzistamatiou T, Mermelekas G, Zoidakis J, Vlahou A, Stavropoulos-Giokas C. Evaluation of Peripheral Blood and Cord Blood Platelet Lysates in Isolation and Expansion of Multipotent Mesenchymal Stromal Cells. Bioengineering (Basel). 2018 Feb 26;5(1). pii: E19. doi: 10.3390/bioengineering5010019.

Barbouti A, Evangelou K, Pateras IS, Papoudou-Bai A, Patereli A, Stefanaki K, Rontogianni D, Muñoz-Espín D, Kanavaros P, Gorgoulis VG. In situ evidence of cellular senescence in Thymic Epithelial Cells (TECs) during human thymic involution. Mech Ageing Dev. 2018 Feb 25. pii: S0047-6374(17)30300-7. doi: 10.1016/j.mad.2018.02.005. [Epub ahead of print]

Pliatska M, Kapasa M, Kokkalis A, Polyzos A, Thanos D. The histone variant macroH2A blocks cellular reprogramming by inhibiting mesenchymal-to-epithelial transition. Mol Cell Biol. 2018 Feb 26. pii: MCB.00669-17. doi: 10.1128/MCB.00669-17. [Epub ahead of print]

Simitsi A, Koros C, Moraitou M, Papagiannakis N, Antonellou R, Bozi M, Angelopoulou E, Stamelou M, Michelakakis H, Stefanis L. Phenotypic Characteristics in GBA-Associated Parkinson's Disease: A Study in a Greek Population. J Parkinsons Dis. 2018;8(1):101-105. doi: 10.3233/JPD-171221.

Cooks T, Pateras IS, Jenkins LM, Patel KM, Robles AI, Morris J, Forshew T, Appella E, Gorgoulis VG, Harris CC. Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246. Nat Commun. 2018 Feb 22;9(1):771. doi: 10.1038/s41467-018-03224-w.

Antoniou N, Vlachakis D, Memou A, Leandrou E, Valkimadi PE, Melachroinou K, Re DB, Przedborski S, Dauer WT, Stefanis L, Rideout HJ. A motif within the armadillo repeat of Parkinson's-linked LRRK2 interacts with FADD to hijack the extrinsic death pathway. Sci Rep. 2018 Feb 22;8(1):3455. doi: 10.1038/s41598-018-21931-8.

Tsangaris GT, Anagnostopoulos AK. Pediatric brain tumors: Update of proteome-based studies. J Proteomics. 2018 Feb 19. pii: S1874-3919(18)30065-4. doi: 10.1016/j.jprot.2018.02.016. [Epub ahead of print] Review.

Tsoukalas C, Geninatti-Crich S, Gaitanis A, Tsotakos T, Paravatou-Petsotas M, Aime S, Jiménez-Juárez R, Anagnostopoulos CD, Djanashvili K, Bouziotis P. Tumor Targeting via Sialic Acid: [68Ga]DOTA-en-pba as a New Tool for Molecular Imaging of Cancer with PET. Mol Imaging Biol. 2018 Feb 20. doi: 10.1007/s11307-018-1176-0. [Epub ahead of print]

Kodela E, Moysidou M, Karaliota S, Koutmani Y, Tsakanikas P, Kodella K, Karavia EA, Kypreos KE, Kostomitsopoulos N, Karalis KP. Strain-specific Differences in the Effects of Lymphocytes on the Development of Insulin Resistance and Obesity in Mice. Comp Med. 2018 Feb 1;68(1):15-24.

Calciolari E, Ravanetti F, Strange A, Mardas N, Bozec L, Cacchioli A, Kostomitsopoulos N, Donos N. Degradation pattern of a porcine collagen membrane in an in vivo model of guided bone regeneration. J Periodontal Res. 2018 Feb 15. doi: 10.1111/jre.12530. [Epub ahead of print]PMID: 29446096

Kodela E, Moysidou M, Karaliota S, Koutmani Y, Tsakanikas P, Kodella K, Karavia EA, Kypreos KE, Kostomitsopoulos N, Karalis KP. Strain-specific Differences in the Effects of Lymphocytes on the Development of Insulin Resistance and Obesity in Mice. Comp Med. 2018 Feb 1;68(1):15-24.PMID: 29460717

Tsoukalas C, Geninatti-Crich S, Gaitanis A, Tsotakos T, Paravatou-Petsotas M, Aime S, Jiménez-Juárez R, Anagnostopoulos CD, Djanashvili K, Bouziotis P. Tumor Targeting via Sialic Acid: [68Ga]DOTA-en-pba as a New Tool for Molecular Imaging of Cancer with PET. Mol Imaging Biol. 2018 Feb 20. doi: 10.1007/s11307-018-1176-0. [Epub ahead of print]PMID: 29464496

Tsangaris GT, Anagnostopoulos AK. Pediatric brain tumors: Update of proteome-based studies. J Proteomics. 2018 Feb 19. pii: S1874-3919(18)30065-4. doi: 10.1016/j.jprot.2018.02.016. [Epub ahead of print] Review.PMID: 29471057

Antoniou N, Vlachakis D, Memou A, Leandrou E, Valkimadi PE, Melachroinou K, Re DB, Przedborski S, Dauer WT, Stefanis L, Rideout H. A motif within the armadillo repeat of Parkinson's-linked LRRK2 interacts with FADD to hijack the extrinsic death pathway. J. Sci Rep. 2018 Feb 22;8(1):3455. doi:10.1038/s41598-018-21931-8.PMID: 29472595 [PubMed - in process]   Free PMC

Cooks T, Pateras IS, Jenkins LM, Patel KM, Robles AI, Morris J, Forshew T, Appella E, Gorgoulis VG, Harris CC. Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246. Nat Commun. 2018 Feb 22;9(1):771. doi: 10.1038/s41467-018-03224-w.PMID: 29472616

Simitsi A, Koros C, Moraitou M, Papagiannakis N, Antonellou R, Bozi M, Angelopoulou E, Stamelou M, Michelakakis H, Stefanis L. Phenotypic Characteristics in GBA-Associated Parkinson's Disease: A Study in a Greek Population. J Parkinsons Dis. 2018;8(1):101-105. doi: 10.3233/JPD-171221.PMID: 29480223

Pliatska M, Kapasa M, Kokkalis A, Polyzos A, Thanos D. The histone variant macroH2A blocks cellular reprogramming by inhibiting mesenchymal-to-epithelial transition. Mol Cell Biol. 2018 Feb 26. pii: MCB.00669-17. doi: 10.1128/MCB.00669-17. [Epub ahead of print]PMID: 29483300

Barbouti A, Evangelou K, Pateras IS, Papoudou-Bai A, Patereli A, Stefanaki K, Rontogianni D, Muñoz-Espín D, Kanavaros P, Gorgoulis VG. In situ evidence of cellular senescence in Thymic Epithelial Cells (TECs) during human thymic involution. Mech Ageing Dev. 2018 Feb 25. pii: S0047-6374(17)30300-7. doi:10.1016/j.mad.2018.02.005. [Epub ahead of print]PMID: 29490231

Christou I, Mallis P, Michalopoulos E, Chatzistamatiou T, Mermelekas G, Zoidakis J, Vlahou A, Stavropoulos-Giokas C. Evaluation of Peripheral Blood and Cord Blood Platelet Lysates in Isolation and Expansion of Multipotent Mesenchymal Stromal Cells. Bioengineering (Basel). 2018 Feb 26;5(1). pii: E19. doi: 10.3390/bioengineering5010019.PMID: 29495420 [PubMed]   Free Article

Reebye V, Huang KW, Lin V, Jarvis S, Cutilas P, Dorman S, Ciriello S, Andrikakou P, Voutila J, Saetrom P, Mintz PJ, Reccia I, Rossi JJ, Huber H, Habib R, Kostomitsopoulos N, Blakey DC, Habib NA. Gene activation of CEBPA using saRNA: preclinical studies of the first in human saRNA drug candidate for liver cancer. Oncogene. 2018 Mar 7. doi: 10.1038/s41388-018-0126-2. [Epub ahead of print]PMID: 29511346

Moysidou M, Karaliota S, Kodela E, Salagianni M, Koutmani Y, Katsouda A, Kodella K, Tsakanikas P, Ourailidou S, Andreakos E, Kostomitsopoulos N, Skokos D, Chatzigeorgiou A, Chung KJ, Bornstein S, Sleeman MW, Chavakis T, Karalis KP. CD8+ T cells in beige adipogenesis and energy homeostasis. JCI Insight. 2018 Mar 8;3(5). pii: 95456. doi: 10.1172/jci.insight.95456. [Epub ahead of print]PMID: 29515042

Chaniotakis I, Antoniou E, Kostomitsopoulos N, Karapsias S, Mirilas P, Salakos C. Stress response to ovariohysterectomy in rabbits: role of anaesthesia and surgery. J Obstet Gynaecol. 2018 Mar 8:1-5. doi: 10.1080/01443615.2017.1400523. [Epub ahead of print]PMID: 29519176

Kalogeropulou AF, Zhao J, Bolliger MF, Memou A, Narasimha S, Molitor TP, Wilson WH, Rideout HJ, Nichols RJ. p62/SQSTM1 is a novel Leucine Rich Repeat Kinase 2(LRRK2) substrate that enhances neuronal toxicity.  Biochem J. 2018 Mar 8. pii: BCJ20170699. doi: 10.1042/BCJ20170699. [Epub ahead of print]PMID: 29519959

Semitekolou M, Xanthou G. ALCAM: A Novel Regulator of Allergic Inflammation in the Airways.  Am J Respir Crit Care Med. 2018 Mar 9. doi: 10.1164/rccm.201801-0196ED. [Epub ahead of print] No abstract available. PMID: 29522354 

Kapodistria K, Tsilibary EP, Kotsopoulou E, Moustardas P, Kitsiou P. Liraglutide, a human glucagon-like peptide-1 analogue, stimulates AKT-dependent survival signalling and inhibits pancreatic β-cell apoptosis.  J Cell Mol Med. 2018 Mar 10. doi: 10.1111/jcmm.13259. [Epub ahead of print]PMID: 29524296

Komseli ES, Pateras IS, Krejsgaard T, Stawiski K, Rizou SV, Polyzos A, Roumelioti FM, Chiourea M, Mourkioti I, Paparouna E, Zampetidis CP, Gumeni S, Trougakos IP, Pefani DE, O'Neill E, Gagos S, Eliopoulos AG, Fendler W, Chowdhury D, Bartek J, Gorgoulis VG. A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced senescence. BMC Genomics. 2018 Jan 10;19(1):37.

Brili S, Oikonomou E, Antonopoulos AS, Pianou N, Georgakopoulos A, Koutagiar I, Kafouris P, Stroumpouli E, Dounis C, Metaxas M, Spyrou G, Anagnostopoulos CD, Tousoulis D. 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomographic Imaging Detects Aortic Wall Inflammation in Patients With Repaired Coarctation of Aorta. Circ Cardiovasc Imaging. 2018 Jan;11(1):e007002. doi: 10.1161/CIRCIMAGING.117.007002.

Kassari P, Papaioannou P, Billiris A, Karanikas H, Eleftheriou S, Thireos E, Manios Y, Chrousos GP, Charmandari E. Electronic registry for the management of childhood obesity in Greece.  Eur J Clin Invest. 2018 Jan 11. doi: 10.1111/eci.12887.

Alissafi T, Kourepini E, Simoes DCM, Paschalidis N, Aggelakopoulou M, Sparwasser T, Boon L, Hammad H, Lambrecht BN, Panoutsakopoulou V. Osteopontin Promotes Protective Antigenic Tolerance against Experimental Allergic Airway Disease.  J Immunol. 2018 Feb 15;200(4):1270-1282. doi: 10.4049/jimmunol.1701345.

Marinou M, Platis D, Ataya FS, Chronopoulou E, Vlachakis D, Labrou NE. Structure-based design and application of a nucleotide coenzyme mimetic ligand: Application to the affinity purification of nucleotide dependent enzymes.  J Chromatogr A. 2018 Feb 2;1535:88-100. doi: 10.1016/j.chroma.2018.01.009. Epub 2018 Jan 3.

Karamanou M, Tsoucalas G, Pantos K, Androutsos G. Isolating colchicine in 19th century: an old drug revisited. Curr Pharm Des. 2018 Jan 14. doi:10.2174/1381612824666180115105850. [Epub ahead of print]
 
Szczesny B, Marcatti M, Ahmad A, Montalbano M, Brunyánszki A, Bibli SI, Papapetropoulos A, Szabo C. Mitochondrial DNA damage and subsequent activation of Z-DNA binding protein 1 links oxidative stress to inflammation in epithelial cells. Sci Rep. 2018 Jan 17;8(1):914. doi: 10.1038/s41598-018-19216-1.

Mavrogenis AF, Markatos K, Nikolaou V, Gartziou-Tatti A, Soucacos PN. Congenital anomalies of the limbs in mythology and antiquity. Int Orthop. 2018 Jan 21. doi: 10.1007/s00264-018-3776-3. [Epub ahead of print] Review.

Papadaki E, Fanouriakis A, Kavroulakis E, Karageorgou D, Sidiropoulos P, Bertsias G, Simos P, Boumpas DT. Response to letter: 'Response to: 'Neuropsychiatric lupus or not? Cerebral hypoperfusion by perfusion-weighted MRI in normal-appearing white matter in primary neuropsychiatric lupus erythematosus' by Papadaki et al' by Wallace. Ann Rheum Dis. 2018 Jan 23. pii: annrheumdis-2018-212949. doi: 10.1136/annrheumdis-2018-212949. [Epub ahead of print]

Michailidou S, Tsangaris G, Fthenakis GC, Tzora A, Skoufos I, Karkabounas SC, Banos G, Argiriou A, Arsenos G. Genomic diversity and population structure of three autochthonous Greek sheep breeds assessed with genome-wide DNA arrays.  Mol Genet Genomics. 2018 Jan 25. doi: 10.1007/s00438-018-1421-x. [Epub ahead of print]

Pipikos T, Kapelouzou A, Tsilimigras DI, Fostinis Y, Pipikou M, Theodorakos A, Pavlidis AN, Kontogiannis C, Cokkinos DV, Koutelou M. Stronger correlation with myocardial ischemia of high-sensitivity troponin T than other biomarkers. J Nucl Cardiol. 2018 Jan 29. doi: 10.1007/s12350-018-1199-6. [Epub ahead of print]

Billiard F, Karaliota S, Wang B, Stellas D, Serafimidis I, Manousopoulou A, Koutmani Y, Ninou E, Golubov J, DaNave A, Tsakanikas P, Xin Y, Zhang W, Sleeman M, Yancopoulos GD, Murphy AJ, Garbis SD, Karalis K, Skokos D. Delta-like Ligand-4-Notch Signaling Inhibition Regulates Pancreatic Islet Function and Insulin Secretion. Cell Rep. 2018 Jan 23;22(4):895-904. doi: 10.1016/j.celrep.2017.12.076. Epub 2018 Jan 28.

Papageorgiou L, Vlachakis C, Dragoumani K, Raftopoulou S, Brouzas D, Nicolaides NC, Chrousos GP, Charmandari E, Megalooikonomou V, Vlachakis D. HCV genetics and genotypes dictate future antiviral strategies. J Mol Biochem. 2017;6:33-40. Epub 2017 Dec 10

Vlachakis D, Zacharaki EI, Tsiamaki E, Koulouri M, Raftopoulou S, Papageorgiou L, Chrousos GP, Ellul J, Megalooikonomou V. Insights into the molecular mechanisms of stress and inflammation in ageing and frailty of the elderly. J Mol Biochem. 2017;6:41-44. Epub 2017 Dec 10.

Markatos K, Papaioannou A, Karamanou M, Androutsos G. The death of the Byzantine Emperor John II Komnenos (1087-1143). Acta Chir Belg. 2018 Feb 1:1-5. doi: 10.1080/00015458.2018.1434108.

Pappa KI, Kontostathi G, Lygirou V, Zoidakis J, Anagnou NP. Novel structural approaches concerning HPV proteins: Insight into targeted therapies for cervical cancer (Review). Oncol Rep. 2018 Feb 9. doi: 10.3892/or.2018.6257.[Epub ahead of print]

Papapetropoulos A, Szabo C. Inventing new therapies without reinventing the wheel: the power of drug repurposing. Br J Pharmacol. 2018 Jan;17 5(2):165-167. doi: 10.1111/bph.14081.PMID: 29313889

Markatos K, Korres D, Chytas D, Karamanou M, Sourlas I, Androutsos G, Mavrogenis A. Apollonius of Citium (first century BC) and his work on the treatment of joint dislocations. Int Orthop. 2018 Jan 8. doi: 10.1007/s00264-017-3751-4.

Andreadou I, Efentakis P, Balafas E, Togliatto G, Davos CH, Varela A, Dimitriou CA, Nikolaou PE, Maratou E, Lambadiari V, Ikonomidis I, Kostomitsopoulos N, Brizzi MF, Dimitriadis G, Iliodromitis EK. Empagliflozin Limits Myocardial Infarction in Vivo and Cell Death in Vitro: Role of STAT3, Mitochondria, and Redox Aspects.  Front Physiol. 2017 Dec 19;8:1077. doi: 10.3389/fphys.2017.01077

Taraslia V, Lymperi S, Pantazopoulou V, Anagnostopoulos AK, Papassideri IS, Basdra EK, Bei M, Kontakiotis EG, Tsangaris GT, Stravopodis DJ, Anastasiadou E. A High-Resolution Proteomic Landscaping of Primary Human Dental Stem Cells: Identification of SHED- and PDLSC-Specific Biomarkers. Int J Mol Sci. 2018 Jan 5;19(1). pii: E158. doi: 10.3390/ijms19010158.PMID: 29304003

Refolo V, Bez F, Polissidis A, Kuzdas-Wood D, Sturm E, Kamaratou M, Poewe W, Stefanis L, Angela Cenci M, Romero-Ramos M, Wenning GK, Stefanova N. Progressive striatonigral degeneration in a transgenic mouse model of multiple system atrophy: translational implications for interventional therapies.  Acta Neuropathol Commun. 2018 Jan 3;6(1):2. doi: 10.1186/s40478-017-0504-y.PMID: 29298733

Rigas P. Up states-based developmental trajectories of the autistic cerebral cortex. Front Biosci (Landmark Ed). 2018 Mar 1;23:1465-1486.PMID: 29293445

Marx D, Metzger J, Pejchinovski M, Gil RB, Frantzi M, Latosinska A, Belczacka I, Heinzmann SS, Husi H, Zoidakis J, Klingele M, Herget-Rosenthal S. Proteomics and Metabolomics for AKI Diagnosis. Semin Nephrol. 2018 Jan;38(1):63-87. doi: 10.1016/j.semnephrol.2017.09.007. Review.PMID: 29291763

Tsaraklis A, Karamanou M, Androutsos G, Skandalakis P, Venieratos D. Preventing syphilis in the 16th century: the distinguished Italian anatomist Gabriele Falloppio (1523-1562) and the invention of the condom. Infez Med. 2017 Dec 1;24(4):395-398.PMID: 29286023 [PubMed - in process] 

Ziogas DE, Kyrochristos ID, Roukos DH. Next-generation sequencing: from conventional applications to breakthrough genomic analyses and precision oncology. Expert Rev Med Devices. 2018 Jan;15(1):1-3. doi: 10.1080/17434440.2017.1419059. Epub 2017 Dec 28. No abstract available. PMID: 29284319

Petsepe DC, Kourkoulis SK, Papadodima SA, Sokolis DP. Regional and age-dependent residual strains, curvature, and dimensions of the human ureter. Proc Inst Mech Eng H. 2017 Dec 1:954411917750192. doi: 10.1177/0954411917750192. [Epub ahead of print]PMID: 29278079

Damaskos C, Tomos I, Garmpis N, Karakatsani A, Dimitroulis D, Garmpi A, Spartalis E, Kampolis CF, Tsagkari E, Loukeri AA, Margonis GA, Spartalis M, Andreatos N, Schizas D, Kokkineli S, Antoniou EA, Nonni A, Tsourouflis G, Markatos K, Kontzoglou K, Kostakis A, Tomos P. Histone Deacetylase Inhibitors as a Novel Targeted Therapy Against Non-small Cell Lung Cancer: Where Are We Now and What Should We Expect? Anticancer Res. 2018 Jan;38(1):37-43. Review.PMID: 29277754

Bonou M, Kapelios CJ, Samarkos M, Benetos G, Tampaki M, Pianou N, Georgakopoulos A, Moyssakis I, Anagnostopoulos C, Barbetseas J. Early diagnosis of right ventricle-pulmonary artery conduit endocarditis by PET/CT. Int J Infect Dis. 2017 Dec 22. pii: S1201-9712(17)30335-1. doi: 10.1016/j.ijid.2017.12.020. [Epub ahead of print] No abstract available. PMID: 29277317

Kosteria I, Tsangaris GT, Gkourogianni A, Anagnostopoulos A, Papadopoulou A, Papassotiriou I, Loutradis D, Chrousos GP, Kanaka-Gantenbein C. Proteomics of Children Born After Intracytoplasmic Sperm Injection Reveal Indices of an Adverse Cardiometabolic Profile. J Endocr Soc. 2017 Feb 27;1(4):288-301. doi: 10.1210/js.2016-1052. eCollection 2017 Apr 1.PMID: 29264487