Publications

1. Stergiopoulos A and Politis PK*. (2016). Nuclear receptor NR5A2 controls neural stem cell fate decisions during development. Nature Communications. 7:12230.
           *Corresponding author.
    
2. Arvaniti E, Vakrakou A, Kaltezioti V, Stergiopoulos A, Prakoura N, Politis PK*, Charonis A*. (2016). Nuclear receptor NR5A2 is involved in the calreticulin gene regulation during renal fibrosis. Biochim Biophys Acta. 1862:1774-1785.
           *Corresponding authors.
    
3. Arvaniti E, Moulos P, Vakrakou A, Chatziantoniou C, Chadjichristos C, Kavvadas P, Charonis A*, Politis PK*. (2016). Whole-transcriptome analysis of UUO mouse model of renal fibrosis reveals new molecular players in kidney diseases. Scientific Reports. 6:26235. 
           *Corresponding authors.
    
4. Fouka P, Alexopoulos H, Chatzi I, Dedos SG, Samiotaki M, Panayotou G, Politis P, Tzioufas A, Dalakas MC. (2016). Antibodies to inositol 1,4,5-triphosphate receptor 1 in patients with cerebellar disease. Neurology: Neuroimmunology & Neuroinflammation. 4(1):e306
    
5. Bunk EC, Ertaylan G, Ortega F, Pavlou MA, Gonzalez Cano L, Stergiopoulos A, Safaiyan S, Völs S, van Cann M, Politis PK, Simons M, Berninger B, Del Sol A, Schwamborn JC. (2016). Prox1 is required for oligodendrocyte cell identity in adult neural stem cells of the subventricular zone. Stem Cells. 34:2115-2129.
    
6. Dermentzaki G, Paschalidis N, Politis PK, Stefanis L. (2016). Complex Effects of the ZSCAN21 Transcription Factor on Transcriptional Regulation of α-Synuclein in Primary Neuronal Cultures and in Vivo. Journal of  Biological Chemistry. 291:8756-8772.
    
7. Alexopoulos H, Kampylafka EI, Fouka P, Tatouli I, Akrivou S, Politis PK, Moutsopoulos HM, Tzioufas AG, Dalakas MC. (2016). Anti-aquaporin-4 autoantibodies in systemic lupus erythematosus persist for years and induce astrocytic cytotoxicity but not CNS disease. Journal of  Neuroimmunology. 289:8-11.
    
8. Aravantinou-Fatorou K, Ortega F, Chroni-Tzartou D. Antoniou N, Poulopoulou C, Politis PK, Berninger B, Matsas R, Thomaidou D (2015). CEND1 and NEUROGENIN2 Reprogram Mouse Astrocytes and Embryonic Fibroblasts to Induced Neural Precursors and Differentiated Neurons. Stem Cell Reports.  5:405-418.
    
9. Fouka P, Alexopoulos H, Akrivou S, Trohatou O, Politis PK, Dalakas MC (2015). GAD65 epitope mapping and search for novel autoantibodies in GAD-associated neurological disorders. Journal of  Neuroimmunology. 281:73-77.
    
10. Kaltezioti K, Antoniou D, Stergiopoulos A, Rozani I, Rohrer H and Politis PK* (2014). Prox1 regulates Olig2 expression to modulate binary fate decisions in spinal cord neurons. The Journal of Neuroscience. 34:15816-15831. 
               *Corresponding author.
     
11. Kapodistria K, Tsilibary E, Politis P, Moustardas P, Charonis A and Paraskevi K (2014). Nephrin, a transmembrane protein, is involved in pancreatic beta-cell survival signaling. Molecular and Cellular Endocrinology. 400:112-128. 
     
12. Stergiopoulos A, Elkouris M and Politis PK* (2014). Prospero-related homeobox 1 (Prox1) at the crossroads of diverse pathways during adult neural fate specification. Frontiers in Cellular Neuroscience, (Review article). 8:454.
              *Corresponding author.
     
13. Antoniou D, Stergiopoulos A and Politis PK (2014). Recent advances in the involvement of long non-coding RNAs in neural stem cell biology and brain pathophysiology. Frontiers in Physiology. 5:155.
              *Corresponding author.
     
14. Missitzi J, Gentner R, Missitzi A, Geladas N, Politis P, Klissouras V and Classen J (2013). Heritability of motor control and motor learning. Physiological Reports. 17: 1(7):e00188. IF: pending
     
15. Tsioras K, Papastefanaki F, Politis PK, Matsas R and Gaitanou M. (2013). Functional Interactions between BM88/Cend1, Ran-binding protein M and Dyrk1B kinase affect cyclin D1 levels and cell cycle progression/exit in mouse neuroblastoma cells. PLoS ONE, 8(11):e82172.
     
16. Foskolou IP, Stellas D, Rozani I, Lavigne MD and Politis PK* (2013). Prox1 suppresses the proliferation of neuroblastoma cells via a dual action in p27-Kip1 and Cdc25A. Oncogene, 32(8):947-960. 
              *Corresponding author.
     
17. Stergiopoulos A and Politis PK* (2013). The role of nuclear receptors in controlling the fine balance between proliferation and differentiation of neural stem cells. Archives of Biochemistry and Biophysics. (Review article). 534(1-2):27-37.
              *Corresponding author.
     
18. Koutmani Y, Politis PK, Elkouris M, Agrogiannis G, Kemerli M, Patsouris E, Remboutsika E, Karalis KP (2013). Corticotropin-releasing hormone exerts direct effects on neuronal progenitor cells: implications for neuroprotection. Molecular Psychiatry. 18(3):300-307.
     
19. Prakoura N, Politis PK, Ihara Y, Michalak M, Charonis AS. (2013). Epithelial Calreticulin Up-Regulation Promotes Profibrotic Responses and Tubulointerstitial Fibrosis Development. Am J Pathol. 183(5):1474-1487.
     
20. Karagianni F, Kaltsa G, Prakoura N, Politis PK, Kaltezioti V, Psarras S, Pagakis S, Katsimboulas M, Chatziantoniou C and Charonis A (2013). Transgelin up-regulation in Obstructive Nephropathy. PLoS ONE. 8(6):e66887.
     
21. Taka S, Gazouli M, Politis PK, Pappa KI, Anagnou NP (2012). Transcription factor ATF-3 regulates allele variation phenotypes of the human SLC11A1 gene. Mol Biol Rep. 40(3):2263-71.
     
22. Elkouris M, Balaskas N, Poulou M, Politis PK, Panayiotou E, Malas S, Thomaidou D, Remboutsika E (2011). Sox1 Maintains the Undifferentiated State of Cortical Neural Progenitor Cells Via the Suppression of Prox1-Mediated Cell Cycle Exit and Neurogenesis. Stem Cells. 29(1), 89-98.
     
23. Kaltezioti V, Kouroupi G, Oikonomaki M, Mantouvalou E, Stergiopoulos A, Charonis A, Rohrer H, Matsas R and Politis PK* (2010). Prox1 regulates the Notch1-mediated inhibition of neurogenesis. PLoS Biology. 8(12):e1000565.
               *Corresponding author. 
    This article from my group was selected for evaluation by the Faculty 1000 (http://f1000.com/8646957)
     
24. Missitzi J, Gentner R, Geladas N, Politis P, Karandreas N, Classen J, and Klissouras V (2011). Plasticity in human motor cortex is in part genetically determined. Journal of Physiology. 589(Pt 2), 297-306.
     
25. Alberti A, Karamessinis P, Peroulis M, Kypreou K, Kavvadas P, Paggakis S, Politis PK and Charonis A (2009). ERp46 is reduced by high glucose and regulates insulin content in pancreatic beta-cells. American Journal of Physiology & Endocrinology. 297, 812-821.
     
26. Kypreou KP, Kavvadas P, Karamessinis P, Peroulis M, Alberti A, Sideras P, Psarras S, Capetanaki Y, Politis PK AND Charonis AS (2008). Altered expression of calreticulin during the development of fibrosis. Proteomics. 8, 2407-2419.
     
27. Politis PK*, Thomaidou D, Matsas R* (2008). Co-ordination of cell cycle exit and differentiation of neuronal progenitors. Cell Cycle. 7, 691-697.
              *Corresponding authors.
     
28. Politis PK*, Akrivou S, Hurel C, Papadodima O, Matsas R (2008). BM88/Cend1 is involved in histone deacetylase inhibition-mediated growth arrest and differentiation of neuroblastoma cells. FEBS Letters. 582, 741-748.
               *Corresponding author.
     
29. Politis PK, Makri G, Thomaidou D, Geissen M, Rohrer H, Matsas R (2007). BM88/Cend1 regulates cell cycle exit and differentiation of neuronal precursors. Proc Natl Acad Sci U S A, 104, 17861–17866.
     
30. Politis PK, Rohrer H, Matsas R (2007). Expression pattern of BM88 in the developing nervous system of the chick and mouse embryo. Gene Expression Patterns 7, 165-177.
     
31. Georgopoulou N*, Hurel C*, Politis PK*, Gaitanou M, Matsas R, Thomaidou D (2006). BM88 is a dual function molecule inducing cell cycle exit and neuronal differentiation of neuroblastoma cells via cyclin D1 down-regulation and retinoblastoma protein hypophosphorylation. The Journal of Biological Chemistry 281, 33606-33620.  
                *equal first authors.
     
32. Martinez-Campa C, Politis P, Moreau JL, Kent N, Goodall J, Mellor J and Goding CR (2004). Precise nucleosome positioning and the TATA box dictate requirements for histone H4 tail and the bromodomain Bdf1. Molecular Cell 15, 69-81.
     
33. Kent NA, Karabetsou N, Politis PK and Mellor J (2001). In vivo chromatin remodelling by yeast ISWI homologs Isw1p and Isw2p. Genes & Development 15, 619-626.
     
34. Kozlov IA, Politis PK, Van Aerschot A, Busson R, Herdewijn P and Orgel LE (1999). Nonenzymatic synthesis of RNA and DNA oligomers on hexitol nucleic acid templates: the importance of the A structure. Journal of the American Chemical Society 121(12), 2653-2656.
     
35. Kozlov IA, Politis PK,, Pitsch S, Herdewijn P and Orgel LE (1999). A highly enantio-selective hexitol nucleic acid template for nonenzymatic oligoguanylate synthesis. Journal of the American Chemical Society 121(5), 1108-1109.
     

Book Chapter

1. Thomaidou D, Politis PK, Matsas R (2010). Neurogenesis in the central nervous system: cell cycle progression/exit and differentiation of neuronal progenitors. Chapter in the Book: Cell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems. Springer. ISBN 978-1-60327-152-3