BRFAA - Biomedical Research Foundation Academy Of Athens
Biomedical Research Foundation Academy Of AthensAcademy Of Athens


Charmandari E, Kino T, Souvatzoglou E, Vottero A, Bhattacharayya N, Chrousos GP. Natural Glucocorticoid Receptor Mutants Causing Glucocorticoid Resistance: Molecular Genotype, Genetic Transmission and Clinical Phenotype. J. Clin. Endocrinol. Metab. 2004; 89: 1939-1949.

Charmandari E, Merke DP, Negro PJ, Keil MF, Martinez PE, Haim A, Gold PW, Chrousos GP. Endocrinologic and psychologic evaluation of 21-hydroxylase deficiency carriers and matched normal subjects: evidence for physical and/or psychologic vulnerability to stress. J. Clin. Endocrinol. Metab. 2004; 89: 2228-2236.

Kino T, Liu SH, Charmandari E, Chrousos GP. Clucocorticoid receptor mutants demonstrate increased motility inside the nucleus of living cells: Time of fluorescence recovery after photobleaching (FRAP) is an integrated measure of receptor function. Mol. Med. 2004; 10: 80-88.

Charmandari E, Chrousos GP, Ichijo T, Bhattacharyya N, Vottero A, Souvatzoglou E, Kino T. The human glucocorticoid receptor (GR) β isoform suppresses the transcriptional activity of GRα by interfering with formation of active coactivator complexes. Mol. Endocrinol. 2005; 19: 52-64.

Kino T, De Martino MU, Charmandari E, Outas T, Ichijo T, Pavlakis GN, Chrousos GP. The human immunodeficiency virus type-1 (HIV-1) accessory protein Vpr inhibits the effect of insulin on the Foxo subfamily of Forkhead transcription factors by interfering with their binding to 14-3-3 proteins: Potential clinical implications regarding the insulin resistance of HIV-1-infected patients. Diabetes 2005; 54: 23-31.

Kino T, Ichijo T, Tiulpakov A, Chheng L, Kozasa T, Chrousos GP. The GTP-binding (G) Protein β Interacts with the Activated Glucocorticoid Receptor and Suppresses Its Transcriptional Activity in the Nucleus. J. Cell. Biol. 2005; 20; 169(6):885-96.

Charmandari E, Raji A, Kino T, Ichijo T, Tiulpakov A, Zachman K, Chrousos GP. A novel point mutation in the ligand-binding domain (LBD) of the human glucocorticoid receptor (hGR) causing generalized glucocorticoid resistance: The importance of C-terminus of hGR LBD in conferring transactivational activity. J. Clin. Endocrinol. Metab. 2005; 90: 3696-3705.

Samara A, Maggi R. Direct submission of rattus norvegicus 24-dehydrocholesterol reductase (Dhcr24) mRNA complete cds. 2005; NCBI accession # AY921220.

Charmandari E, Kino T, Ichijo T, Zachman K, Alatsatianos A, Chrousos GP. Functional characterization of the natural human glucocorticoid receptor (hGR) mutants hGRαR477H and hGRαG679S associated with generalized glucocorticoid resistance. J. Clin. Endocrinol. Metab. 2006; 91: 1535-1543.

Charmandari E, Kino T, Ichijo T, Jubiz W, Mejia L, Zachman K, Chrousos GP. A novel point mutation in helix11 of the ligand-binding domain of the human glucocorticoid receptor gene causing generalized glucocorticoid resistance J. Clin. Endocrinol. Metab. 2007; 92: 3986-90.

Zoumakis E, Grammatopoulos DK, Chrousos GP. Corticotropin-releasing hormone receptor antagonists. Eur. J. Endocrinol. 2006; 155: S85-S91.

Zoumakis E, Kalantaridou SN, Chrousos GP. The brain-skin connection: nerve growth factor-dependent pathways for stress-induced skin disorders. J. Mol. Med. 2007; (Epub ahead of print).

Doufexis M, Storr HL, King PJ, Clark AJ. Interaction of the melanocortin 2 receptor with nucleoporin 50: evidence for a novel pathway between a G-protein-coupled receptor and the nucleus. FASEB J. 2007; (Epub ahead of print).

Kino T, Ichijo T, Amin ND, Kesavapany S, Wang Y, Kim N, Rao S, Player A, Zheng YL, Garabedian MJ, Kawasaki E, Pant HC, Chrousos GP. Cyclin-dependent kinase 5 differentially regulates the transcriptional activity of the glucocorticoid receptor through phosphorylation: Clinical implications for the nervous system response to glucocorticoids and stress. Mol. Endocrinol. 2007; (in press).