Ref:  2023  / 17 -10-2012
 

Early Stage Research Positions in the context of the Marie Curie European Industrial Doctorate (EID) program BCMolMed.

This offer for 3 PhD positions (ESR1-3) is part of the FP7 EID (European Industrial Doctorate program) BCMolMed, which integrates multi-disciplinary expertise from academic and industrial investigators as state of the art training platform on biomarker research and systems biology. The program specifically involves the application of state of the art -omics technologies to investigate biomarkers for bladder cancer recurrence and progression and includes; identifying and testing candidate molecules as well as application of systems biology approaches to decipher molecular pathology and understanding clinical phenotypes. The two main partners are Mosaiques Diagnostics (Germany-industrial-Prof Harald Mischak) and BRFAA (Greece-academic- Dr Antonia Vlahou). The candidate will be seconded by both partners and spend at least 50% of their time in the industrial partner, as outlined in the grant agreement and will be supervised closely by both partners. Short secondments to the 4 associate partners may be also foreseen, as applicable.
 

ESR1

Description

The proposed project targets the evaluation of association of known or suspected biomarkers with bladder cancer. Specific objectives include:

1. Validation of biomarkers significantly associated with bladder cancer aggressiveness in biological samples
2. Identification of the functional relevance of these biomarkers in bladder cancer in cell line and animal models.

The ESR will receive training in CE-MS and Elisa, statistical analysis of data as well as basic molecular biology techniques, animal use and handling.
This ambitious research program should lead the student to the successful completion of a doctoral degree in a highly competitive industrial and academic environment,

Nr of positions available : 1

Research Fields

Proteomics, Molecular Biology

Career Stage

Early stage researcher.

Benefits

The PhD project (36 months) is part of the Marie Curie EID BCMolMed under the salary conditions defined by the program for ESRs

Requirements

We are looking for a highly motivated, enthusiastic junior scientist with a Master's degree or equivalent in a Life Sciences discipline (Biology, Chemistry.). Excellent knowledge of English language (spoken and written) is required. Background in Molecular Biology and experience in fields related to proteomics and mass spectrometry are a plus. The selected candidate will be recruited by Mosaiques Diagnotics and enrolled in a PhD program at the U of Athens, Greece

Excellent research and communication skills, ability to develop initiatives and work in a team, meticulous record keeping, dedicated work and excellent work ethics are essential

Candidates must meet the following criteria: 1) any nationality, but not having resided or carried out their main activity in Germany for more than 1 year in the past 3 years; 2) with a degree that in their country gives access to a PhD; 3) not having completed a PhD.

Comment/web site for additional job details

http://mosaiques-diagnostics.de/diapatpcms/mosaiquescms/front_content.php?idcat=155
http://www.bioacademy.gr/faculty-details/H8M/antonia

To apply, please send a cover letter describing your suitability for the position, detailed CV, and the name and address of two referees to support your application by email to Prof Harald Mischak (mischak@mosaiques-diagnostics.com) and Dr Antonia Vlahou (vlahoua@bioacademy.gr) by October 15, 2012. An extension of the deadline may occur and the call will remain open until a suitable candidate is selected.

Following the guidelines of the European Commission's Roadmap for Equality between Women and Men (2007) and of the European Council's Pact for Gender Equality (2006), the BCMolMed management team supports the effort towards promoting representation of women in the European Research area, and therefore invites applications by women.
Among equally qualified applicants women will receive preferential consideration.

ESR2:

Description
The proposed project targets the identification of new bladder cancer biomarkers focusing on extracellular matrix (ECM) and cell secretome

The specific aims include:

1. Identification of ECM proteins significantly affected in bladder cancer
2. Identification of specific matrix metalloproteinases (MMPs) involved in bladder cancer invasion and metastasis

Tissue and cell line models for the disease will be analyzed by a series of proteomics and genomics (in the case of MMPs) approaches.
The ESR will receive training in a variety of protein separation, identification and quantification techniques as well as statistical analysis of data.
This ambitious research program should lead the student to the successful completion of a doctoral degree in a highly competitive industrial (MOS) and academic (BRFAA) environment.

Nr of positions available: 1

Research Fields

Proteomics, Analytical Chemistry, Mass Spectrometry, Genomics

Career Stage

Early stage researcher.

Benefits

The PhD project (36months) is part of the Marie Curie EID BCMolMed under the salary conditions defined by the program for ESRs

Requirements

We are looking for a highly motivated, enthusiastic junior scientist with a Master's degree or equivalent in a Life Sciences discipline (Chemistry, Biology.). Excellent knowledge of English language (spoken and written) is required. Background in protein chemistry, cell line analysis, and experience in fields related to proteomics and mass spectrometry are a plus. The selected candidate will be recruited by BRFAA and enrolled in a PhD program at the U of Athens, Greece

Excellent research and communication skills, ability to develop initiatives and work in a team, meticulous record keeping, dedicated work and excellent work ethics are essential

Candidates must meet the following criteria: 1) any nationality, but not having resided or carried out their main activity in Greece for more than 1 year in the past 3 years; 2) with a degree that in their country gives access to a PhD; 3) not having completed a PhD.

Comment/web site for additional job details
http://mosaiques-diagnostics.de/diapatpcms/mosaiquescms/front_content.php?idcat=155
http://www.bioacademy.gr/faculty-details/H8M/antonia

To apply, please send a cover letter describing your suitability for the position, detailed CV, and the name and address of two referees to support your application by email to Prof Harald Mischak (mischak@mosaiques-diagnostics.com) and Dr Antonia Vlahou (vlahoua@bioacademy.gr) by October 15, 2012. An extension of the deadline may occur and the call will remain open until a suitable candidate is selected.

Following the guidelines of the European Commission's Roadmap for Equality between Women and Men (2007) and of the European Council's Pact for Gender Equality (2006), the BCMolMed management team supports the effort towards promoting representation of women in the European Research area, and therefore invites applications by women.
Among equally qualified applicants women will receive preferential consideration.

ESR3:

Description

The proposed project targets the in silico modeling of bladder cancer cell invasion.

Specific Aims include:

1. Identification of features significantly associated with BC invasion and metastasis,
2. Placing known features and plausible candidates in pathways
3. Develop a model of molecular changes in BC, and validate key elements

The ESR will receive training in a variety of systems biology tools and approaches including tools for existing multi-source data consolidation, text mining, and development of in silico models.  This ambitious research program should lead the student to the successful completion of a doctoral degree in a highly competitive industrial (MOS) and academic (BRFAA) environment.

Nr of positions available: 1

Research Fields

Bioinformatics, Proteomics, Genomics

Career Stage

Early stage researcher.

Benefits

The PhD project (36 months) is part of the Marie Curie EID BCMolMed under the salary conditions defined by the program for ESRs

Requirements

We are looking for a highly motivated, enthusiastic junior scientist with a Master's degree or equivalent in Bioinformatics ideally with a Life Science (Biology) background.  Excellent knowledge of English language (spoken and written) is required.Experience in fields related to-omics is a plus. The selected candidate will be recruited by MOS and enrolled in a PhD program at the U of Athens, Greece

Excellent research and communication skills, ability to develop initiatives and work in a team, meticulous record keeping, dedicated work and excellent work ethics are essential

Candidates must meet the following criteria: 1) any nationality, but not having resided or carried out their main activity in Germany for more than 1 year in the past 3 years; 2) with a degree that in their country gives access to a PhD; 3) not having completed a PhD.

Comment/web site for additional job details

http://mosaiques-diagnostics.de/diapatpcms/mosaiquescms/front_content.php?idcat=155
http://www.bioacademy.gr/faculty-details/H8M/antonia

Interested candidates should submit their CV and details of two referees to the Biomedical Research Foundation (Soranou Efesiou 4, 11527, Athens, Attention: Personnel Department) of the Academy of Athens by the 26th of October, 2012. For further information, please contact Prof Harald Mischak (mischak@mosaiques-diagnostics.com) and Dr Antonia Vlahou (vlahoua@bioacademy.gr).

Following the guidelines of the European Commission's Roadmap for Equality between Women and Men (2007) and of the European Council's Pact for Gender Equality (2006), the BCMolMed management team supports the effort towards promoting representation of women in the European Research area, and therefore invites applications by women.

Among equally qualified applicants women will receive preferential consideration.

THE GENERAL DIRECTOR

ATHANASIOS TSOUROPLIS