Biomedical Research Foundation Academy Of AthensAcademy Of Athens
Scientific Personnel

Despina Despina Sanoudou, PhD, FACMG
University Faculty, Affiliated Investigator

Telephone : +30 210 6597 055
Fax : +30 210 6597 545
e-mail :

Center :

Basic Research

Lab Site :

Kranias & Sanoudou Lab

Brief Bio

Despina Sanoudou is Associate Professor in Pharmacogenomics at the Medical School of the National and Kapodistrian University of Athens, Head of the Clinical Genomics and Pharmacogenomics Unit at the 4th Department of Internal Medicine, and collaborating Faculty at the Biomedical Research Foundation of the Academy of Athens. Her research work focuses on deciphering pathogenetic mechanisms in cardiovascular disease and the development of Precision Medicine therapeutic approaches. She has participated in tens of competitive research projects, funded from international or national organizations, and she is currently the Principal Investigator of the Greek Team for the prestigious International Leducq Research Network “Cure-PLaN”. She has over 100 publications in scientific journals and books, and over 400 oral and written presentations at international meetings. She serves on the evaluation committees of 20 international and national funding organizations, as Associate Editor in the Metabolism journal, in the editorial board and reviewer teams of 50 other international scientific journals. Dr Sanoudou has received multiple awards for her contribution to science including the Greek L’Oreal-UNESCO award, the European Society of Human Genetics, the American Society of Human Genetics, and more. She teaches in multiple postgraduate programs, is the Head of the "Precision Medicine" course of the University of Athens Medical School, and the Founder / Head of the Scientific Outreach Program for High School Students at IIBEAA which has hosted over 5,000 students from public and private schools across Greece.

Selected Publications

The Cardioprotective PKA-Mediated Hsp20 Phosphorylation Modulates Protein Associations Regulating Cytoskeletal Dynamics.
Vafiadaki E, Arvanitis DA, Eliopoulos AG, Kranias EG, Sanoudou D. Int J Mol Sci. 2020 Dec 16;21(24):9572. doi: 10.3390/ijms21249572.

Advances in biological therapies for dyslipidemias and atherosclerosis.
Valanti EK, Dalakoura-Karagkouni K, Siasos G, Kardassis D, Eliopoulos AG, Sanoudou D. Metabolism. 2020 Dec 5;116:154461. doi: 10.1016/j.metabol.2020.154461. Online ahead of print.

The "Virtual Digital Twins" Concept in Precision Nutrition.
Gkouskou K, Vlastos I, Karkalousos P, Chaniotis D, Sanoudou D, Eliopoulos AG. Adv Nutr. 2020 Nov 16;11(6):1405-1413. doi: 10.1093/advances/nmaa089.

Leducq Transatlantic Network of Excellence to Cure Phospholamban-Induced Cardiomyopathy (CURE-PLaN).
Doevendans PA, Glijnis PC, Kranias EG. Circ Res. 2019 Sep 13;125(7):720-724. doi: 10.1161/CIRCRESAHA.119.315077.

The Crocus sativus Compounds trans-Crocin 4 and trans-Crocetin Modulate the Amyloidogenic Pathway and Tau Misprocessing in Alzheimer Disease Neuronal Cell Culture Models.
Chalatsa I, Arvanitis DA, Koulakiotis NS, Giagini A, Skaltsounis AL, Papadopoulou-Daifoti Z, Tsarbopoulos A, Sanoudou D. Front Neurosci. 2019 Mar 26;13:249. doi: 10.3389/fnins.2019.00249.

Muscle Lim Protein and myosin binding protein C form a complex regulating muscle differentiation.
Arvanitis DA, Vafiadaki E, Papalouka V, Sanoudou D. Biochim Biophys Acta Mol Cell Res. 2017 Dec;1864(12):2308-2321. doi: 10.1016/j.bbamcr.2017.08.010.

Calcium/calmodulin-dependent protein kinase II (CaMKII) inhibition ameliorates arrhythmias elicited by junctin ablation under stress conditions.
Tzimas C, Terrovitis J, Lehnart SE, Kranias EG, Sanoudou D. Heart Rhythm. 2015 Jul;12(7):1599-610. doi: 10.1016/j.hrthm.2015.03.043.

Correction of human phospholamban R14del mutation associated with cardiomyopathy using targeted nucleases and combination therapy.
Karakikes I, Stillitano F, Nonnenmacher M, Tzimas C, Sanoudou D, Termglinchan V, Kong CW, Rushing S, Hansen J, Ceholski D, Kolokathis F, Kremastinos D, Katoulis A, Ren L, Cohen N, Gho JMIH, Tsiapras D, Vink A, Wu JC, Asselbergs FW, Li RA, Hulot JS, Kranias EG, Hajjar RJ. Nat Commun. 2015 Apr 29;6:6955. doi: 10.1038/ncomms7955.


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