Biomedical Research Foundation Academy Of AthensAcademy Of Athens
Scientific Personnel

Athanasios Athanasios Tzioufas, MD, PhD
University Faculty, Affiliated Investigator

Telephone : +30 210 6597 338
e-mail :

Center :

Clinical, Experimental Surgery & Translational Research

Lab Site :

Athanasios Tzioufas Lab

Brief Bio

Athanasios G. Tzioufas is a Professor of Pathophysiology and Rheumatology of the Medical School of National and Kapodistrian University of Athens. He received his degree in Medicine from the School of Medicine of the University of Ioannina in 1983, where he also completed his Ph.D in 1989 and his Board of Rheumatology in 1994 (under Professor H. M. Moutsopoulos). During 2006-2007 he served as a visiting scientist in National Institute of Health in the U.S.A.

In 1997 he was elected as an Assistant Professor and in 2003 as an Associate Professor of the Medical School of the University of Athens. In 2010 he was unanimously elected as a Professor of Rheumatology and Immunology in the Medical School of the National and Kapodistrian University of Athens, serving also as the Director of the Clinic and Laboratory of Pathophysiology (2011-2022). During that time, he and his colleagues established Centers of Expertise for Autoimmune and Autoinflammatory Diseases in Laikon General Hospital.

Professor A.G. Tzioufas has organized a numerous of scientific meetings, including the 11th International Symposium of Sjogren’s Syndrome (2011), Summer School of Immunology (2010, 2012, 2014 and 2016) the Joint Scientific Meeting with Johns Hopkins University(2010). He coordinates the joint Rheumatology Academic program of the University of Athens and he is in Steering Committee of the intradepartmental educational program in Rheumatology. He is a member of numerous scientific committees in Greece and abroad. He is member of the Editorial Board in 6 peer reviewed Scientific Journals and a reviewer in another 30 scientific journals. For the last 3 years he had been the President of “Sjogren’s Syndrome” of the American College of Rheumatology.

Professor Tzioufas has supervised or co-supervised more than 30 PhD dissertations in NKUA and participated in the examining committee in more than 40 PhDs in Greece and abroad. He has more than 450 publications in international Peer Reviewed Journals and books with an h-factor 86 and more than 31500 citations (Google Scholar). He has given more than 200 lectures as an Invited Speaker in scientific conferences and Universities in Europe, USA, Latin

Selected Publications

Veroutis D, Argyropoulou OD, Goules AV, Kambas K, Palamidas DA, Evangelou K, Havaki S, Polyzou A, Valakos D, Xingi E, Karatza E, Boki KA, Cavazza A, Kittas C, Thanos D, Ricordi C, Marvisi C, Muratore F, Galli E, Croci S, Salvarani C, Gorgoulis VG, Tzioufas AG. Senescent cells in giant cell arteritis display an inflammatory phenotype participating in tissue injury via IL-6-dependent pathways. Ann Rheum Dis. 2023 Nov 24:ard-2023-224467

Chatzis LG, Stergiou IE, Goules AV, Pezoulas V, Tsourouflis G, Fotiadis D, Tzioufas AG, Voulgarelis M. Clinical picture, outcome and predictive factors of lymphoma in primary Sjögren's syndrome: results from a harmonized dataset (1981-2021). Rheumatology (Oxford). 2022 Aug 30;61(9):3576-3585.

Chatzis L, Goules AV, Pezoulas V, Baldini C, Gandolfo S, Skopouli FN, Exarchos TP, Kapsogeorgou EK, Donati V, Voulgari PV, Mavragani CP, Gorgoulis V, De Vita S, Fotiadis D, Voulgarelis M, Moutsopoulos HM, Tzioufas AG. A biomarker for lymphoma development in Sjogren's syndrome: Salivary gland focus score. J Autoimmun. 2021 Jul;121:102648.

Tzioufas AG, Bakasis AD, Goules AV, Bitzogli K, Cinoku II, Chatzis LG, Argyropoulou OD, Venetsanopoulou AI, Mavrommati M, Stergiou IE, Pezoulas V, Voulgari PV, Katsimpari C, Katechis S, Gazi S, Katsifis G, Sfontouris CI, Georgountzos AI, Liossis SN, Papagoras C, Fotiadis DI, Skopouli FN, Vlachoyiannopoulos PG, Moutsopoulos HM. A prospective multicenter study assessing humoral immunogenicity and safety of the mRNA SARS-CoV-2 vaccines in Greek patients with systemic autoimmune and autoinflammatory rheumatic diseases. J Autoimmun. 2021 Dec;125:102743.

Giacomelli R, Afeltra A, Alunno A, Bartoloni-Bocci E, Berardicurti O, Bombardieri M, Bortoluzzi A, Caporali R, Caso F, Cervera R, Chimenti MS, Cipriani P, Coloma E, Conti F, D'Angelo S, De Vita S, Di Bartolomeo S, Distler O, Doria A, Feist E, Fisher BA, Gerosa M, Gilio M, Guggino G, Liakouli V, Margiotta DPE, Meroni P, Moroncini G, Perosa F, Prete M, Priori R, Rebuffi C, Ruscitti P, Scarpa R, Shoenfeld Y, Todoerti M, Ursini F, Valesini G, Vettori S, Vitali C, Tzioufas AG. Guidelines for biomarkers in autoimmune rheumatic diseases - evidence based analysis. Autoimmun Rev. 2019 Jan;18(1):93-106.

Kapsogeorgou EK, Papageorgiou A, Protogerou AD, Voulgarelis M, Tzioufas AG. Low miR200b-5p levels in minor salivary glands: a novel molecular marker predicting lymphoma development in patients with Sjögren's syndrome. Ann Rheum Dis. 2018 Aug;77(8):1200-1207.

Roccatello D, Saadoun D, Ramos-Casals M, Tzioufas AG, Fervenza FC, Cacoub P, Zignego AL, Ferri C. Cryoglobulinaemia. Nat Rev Dis Primers. 2018 Aug 2;4(1):11.

Brito-Zerón P, Baldini C, Bootsma H, Bowman SJ, Jonsson R, Mariette X, Sivils K, Theander E, Tzioufas A, Ramos-Casals M. Sjögren syndrome. Nat Rev Dis Primers. 2016 Jul 7;2:16047.

Tzioufas AG, Kapsogeorgou EK. Biomarkers. Saliva proteomics is a promising tool to study Sjögren syndrome. Nat Rev Rheumatol. 2015 Apr;11(4):202-3.

Goules AV, Tatouli IP, Moutsopoulos HM, Tzioufas AG. Clinically significant renal involvement in primary Sjögren's syndrome: clinical presentation and outcome. Arthritis Rheum. 2013 Nov;65(11):2945-53.

Hall JC, Casciola-Rosen L, Berger AE, Kapsogeorgou EK, Cheadle C, Tzioufas AG, Baer AN, Rosen A. Precise probes of type II interferon activity define the origin of interferon signatures in target tissues in rheumatic diseases. Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17609-14.

Ramos-Casals M, Tzioufas AG, Stone JH, Sisó A, Bosch X. Treatment of primary Sjögren syndrome: a systematic review. JAMA. 2010 Jul 28;304(4):452-60.


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