Biomedical Research Foundation Academy Of AthensAcademy Of Athens
Scientific Personnel

Dimitrios P. Dimitrios P. Sokolis, PhD
Investigator - Lecturer Level

Telephone : +30 210 6597 370
Fax : +30 210 6597 365
e-mail : dsokolis@bioacademy.gr


Center :

Clinical, Experimental Surgery & Translational Research

Lab Site :

Sokolis Lab


Brief Bio

Dr. Dimitrios P. Sokolis obtained his B.Sc. in Physics from Imperial College of the University of London, UK in 1993. He received his M.Sc. in Engineering and Physical Sciences Applied to Medicine from the same University in 1994, studying mathematical models of convective & diffusive transport processes of macromolecular substances in the arterial wall.

He received his Ph.D. from the Medical School of the University of Athens in 1998, upon examination of the mechanical performance of the aortic wall in health and disease. He received his Ph.D. from the National Technical University of Athens in 2002, having classified systematically and in mathematical terms the elastic materials of the various symmetries. He was a post-doctoral fellow in the Institute for Theoretical and Applied Mechanics of the National Academy of Athens in Theoretical Mechanics, and the Laboratory of Experimental Surgery of the University of Athens Medical School in Biomechanics.

His major research interests focus on the biomechanics of the cardiovascular system, aiming at determining the mechanical response and structure of organs, tissues, and cellular systems of the cardiovascular system in health and disease; the application of techniques for the analysis of structure, such as optical microscopy and stereology; and the assessment of structure-function relationships. He is particularly interested in soft tissue, organ, and cell biomechanics, namely in the constitutive laws of soft tissues; the biomechanical analyses of cells, membranes, and sub-cellular structures; and the growth-remodeling responses in soft tissues. He is also interested in the mechanics of anisotropic materials (biologic, crystalline, composites). He has published 43 papers in International and 11 in Greek Journals. He has presented 48 papers in International and 72 in Greek conferences.

Selected Publications

Theocaris PS, Sokolis DP. Spectral Decomposition of the Linear Elastic Tensor for Monoclinic Symmetry. Acta Crystallographica Section A 55: 635-647, 1999.

Angouras D, Sokolis DP, Dosios T, Kostomitsopoulos N, Boudoulas H, Skalkeas Gr, Karayannacos PE. Effect of Impaired Vasa Vasorum Flow on the Structure and Mechanics of the Thoracic Aorta. Implications for the Pathogenesis of Aortic Dissection. European Journal of Cardio-Thoracic Surgery 17: 468-473, 2000.

Theocaris PS, Sokolis DP. Invariant Elastic Constants and Eigentensors of Orthorhombic, Tetragonal, Hexagonal and Cubic Crystalline Media. Acta Crystallographica Section A 56: 319-331, 2000.

Sokolis DP, Boudoulas H, Karayannacos PE. Assessment of the Aortic Stress-Strain Relation in Uniaxial Tension. Journal of Biomechanics 35: 1213-1223, 2002.

Sokolis DP, Kefaloyannis EM, Kouloukoussa M, Marinos E, Boudoulas H, Karayannacos PE. A Structural Basis for the Aortic Stress-Strain Relation in Uniaxial Tension. Journal of Biomechanics 39: 1651-1662, 2006.

Sokolis DP. Passive Mechanical Properties and Structure of the Aorta: Segmental Analysis. Acta Physiologica 190: 277-289, 2007.

Iliopoulos DC, Kritharis E, Giagini AT, Papadodima S, Sokolis DP. Ascending Thoracic Aortic Aneurysm is Associated with Compositional Remodeling and Vessel Stiffening but not Weakening in Age-Matched Subjects. Journal of Thoracic and Cardiovascular Surgery 137: 101-109, 2009.

Stavropoulou E, Dafalias YF, Sokolis DP. Biomechanical Characteristics and Microstructure of Passive Esophagus: Experimental Investigation and Comparative Constitutive Modeling. Journal of Biomechanics 42: 2654-2663, 2009.

Sokolis DP. A Passive Strain-Energy Function for Elastic and Muscular Arteries: Correlation of Material Parameters with Histological Data. Medical and Biological Engineering and Computing 2010.

Kritharis EP, Kakisis JD, Giagini AT, Manos T, Stergiopulos N, Tsangaris S, Sokolis DP. Biomechanical, Morphological, and Zero-Stress State Characterization of Jugular Vein Remodeling in Arteriovenous Fistulas for Hemodialysis. Biorheology 47: 297-319, 2010.

Sokolis DP, Sassani S, Kritharis EP, Tsangaris S. Differential Histomechanical Response of Carotid Artery in Relation to Species and Region: Mathematical Description Accounting for Elastin and Collagen Anisotropy. Medical and Biological Engineering and Computing 49: 867-79, 2011.

Sokolis DP. Multiaxial Mechanical Behavior of the Passive Ureteral Wall: Experimental Study and Mathematical Characterization. Computer Methods in Biomechanics and Biomedical Engineering 2011 (in press).

 

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