Biomedical Research Foundation Academy Of AthensAcademy Of Athens
Scientific Personnel

Evangelia Evangelia Charmandari, MD, MSc, PhD, MRCP(UK), CCST(UK)
University Faculty, Affiliated Investigator

Telephone : +30 210 6597 196
Fax : +30 210 6597 545
e-mail :

Center :

Clinical, Experimental Surgery & Translational Research

Lab Site :

Chrousos & Charmandari Lab

Brief Bio

Evangelia Charmandari, MD, MSc, PhD, MRCP(UK), CCST(UK)
Professor of Pediatrics - Pediatric Endocrinology
National and Kapodistrian University of Athens Medical School
Aghia Sophia Children’s Hospital

Evangelia Charmandari graduated from the Medical School of the University of Thessaloniki as a valedictorian of her class and completed her specialization in General Pediatrics in the UK. She was further subspecialized in Pediatric and Adolescent Endocrinology at the London Centre for Pediatric Endocrinology and Metabolism, Great Ormond Street Hospital for Children and University College Hospital in London (UK). She is a certified Pediatrician and Pediatric and Adolescent Endocrinologist by the Royal College of Pediatrics and Child Health, London, UK. She obtained a Master of Science in Clinical Pediatrics and a PhD in Pediatric and Adolescent Endocrinology, which were awarded by the University of London (UK). She subsequently undertook a Postdoctoral fellowship in Molecular Endocrinology and Cellular Biology at the National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA. She also worked as a Consultant in Pediatric and Adolescent Endocrinology at St. James' University Hospital and Leeds General Infirmary, Leeds, UK.

In February 2011, Dr. Charmandari joined the faculty of the Medical School of the National and Kapodistrian University of Athens as an Associate Professor, and became Full Professor of Pediatric and Adolescent Endocrinology in 2015. She carries out her clinical and research work at the Division of Endocrinology, Metabolism and Diabetes, First Department of Pediatrics, "Aghia Sophia" Hospital for Children. She is also an Affiliated Investigator of the Biomedical Research Foundation of the Academy of Athens.

She has 314 publications (101 articles in SCI journals, 8 in non-SCI journal, 1 book, 54 chapters in books, and 113 in international conference proceedings, and 37 in national conference proceedings), which have received 6011 citations (h-index=39, Source: Google Scholar, total impact factor=560,377). She was awarded the ‘Henning Andersen Prize’ of the European Society of Pediatric Endocrinology (basic research), as well as several prizes of the Hellenic Endocrine Society. She has been an invited speaker in more than 200 National and International Meetings. Finally, she has attracted 1,680,000.00 research funding as a main Principal Investigator (PI) and 790,000.00 Euros as co-PI.

Selected Publications

Charmandari E, Brook CGD. 20 years of experience in idiopathic central diabetes insipidus. Lancet 1999; 353 (9171): 2212-2213.

Charmandari E, Hindmarsh PC, Johnston A, Brook CGD. Alterations in cortisol pharmacokinetics at puberty. Journal of Clinical Endocrinology & Metabolism 2001; 86(6): 2701-2708.

Charmandari E, Kino T, Souvatzoglou E, Chrousos GP. Pediatric stress: Hormonal mediators and stress response. Hormone Research 2003; 59(4): 161-179.

Charmandari E, Chrousos GP, Ichijo T, Bhattacharyya N, Vottero A, Souvatzoglou E, Kino T. The human glucocorticoid receptor (GR) β isoform suppresses the transcriptional activity of GRα by interfering with formation of active coactivator complexes. Molecular Endocrinology 2005; 19(1): 52-64.

Charmandari E, Tsigos C, Chrousos GP. Endocrinology of the stress response. Annual Reviews of Physiology 2005; 67: 259-284.

Charmandari E, Raji A, Kino T, Ichijo T, Tiulpakov A, Zachman K, Chrousos GP. A novel point mutation in the ligand-binding domain (LBD) of the human glucocorticoid receptor (hGR) causing generalized glucocorticoid resistance: The importance of C-terminus of hGR LBD in conferring transactivational activity. Journal of Clinical Endocrinology & Metabolism 2005; 90(6): 3696-3705.

Kino T, Souvatzoglou E, Charmandari E, Ichijo T, Driggers P, Mayers C, Alatsatianos A, Manoli I, Westphal H, Chrousos GP, Segars JH. RHO family guanine nucleotide exchange factor BRX couples extracellular signals to the glucocorticoid signaling system. Journal of Biological Chemistry 2006; 281(14): 9118-9126.

Charmandari E, Chrousos GP, Lambrou GI, Pavlaki A, Koide H, Ng SSM, Kino T. Peripheral CLOCK regulates target-tissue glucocorticoid receptor transcriptional activity in a circadian fashion in man. PLoS One 2011; 6(9): e25612.

Charmandari E, Sertedaki A, Kino T, Merakou C, Hoffman DA, Hatch MM, Hurt DE, Lin L, Xekouki P, Stratakis CA, Chrousos GP. A novel point mutation in the KCNJ5 gene causing primary hyperaldosteronism and early-onset autosomal dominant hypertension. Journal of Clinical Endocrinology & Metabolism 2012; 97(8): E1532-9.

Charmandari E, Achermann JC, Carel JC, Soder O, Chrousos GP. Stress response and child health. Science Signaling 2012; 5(248): mr1.

Charmandari E, Nicolaides N, Chrousos GP. Adrenal Insufficiency. Lancet 2014; 383(9935): 2152-67.

Kassari P, Papaioannou P, Billiris A, Karanikas H, Eleftheriou S, Thireos E, Manios Y, Chrousos GP, Charmandari E. Electronic Registry for the Management of Childhood Obesity in Greece. European Journal of Clinical Investigation 2018; 48(3). doi: 10.1111/eci.12887.


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