Publications

D. Troumpoukis, A. Papadimitropoulou, C. Charalampous, P. Kogionou, K. Palamaris, P. Sarantis and I. Serafimidis (2022) “Targeting autophagy in pancreatic cancer: The cancer stem cell perspective” Front. Oncol. 12:1049436.

E. Spears*, I. Serafimidis*, A. Powers and A. Gavalas (2021) “Debates in pancreatic beta cell biology: Proliferation versus progenitor differentiation and transdifferentiation in restoring β cell mass” Front. Endocrinol. 12:722250
(*equal contribution)

E. Mameishvili, I. Serafimidis, M. Lesche, S. Iwaskiewicz, S. Reinhardt, M. Büttner, D. Stellas, A. Papadimitropoulou, M. Szabolcs, K. Anastassiadis, A. Dahl, F. Theis, A. Efstratiadis and A. Gavalas (2019) “Aldh1b1 expression marks adult stem cells and is required for Kras-induced pancreatic cancer in mice” Proc. Natl. Acad. Sci. USA 116(41), p20679-88

I. Giannios, I. Serafimidis, V. Anastasiou, D. Pezzola, C. Andree, M. Bickle and A. Gavalas (2019) “Protein methyltransferase inhibition decreases endocrine specification through the upregulation of Adh1b1 expression” Stem Cells 37(5), p640-651

F. Billiard, S. Karaliota, B. Wang, D. Stellas, I. Serafimidis, A. Manousopoulou, Y. Koutmani, E. Ninou, J. Golubov, A. DaNave, P. Tsakanikas, W. Zhang, G. Yancopoulos, A. Murphy, S. Garbis, K. Karalis and D. Skokos (2018) “Delta-like ligand 4 – Notch signalling inhibitor regulates pancreatic islet function and insulin secretion” Cell Rep. 22(4), p895-904

I. Serafimidis, E. Rodriguez-Aznar, M. Lesche, K. Yoshioka, Y. Takuwa, A. Dahl, D. Pan and A. Gavalas (2017) “Pancreas lineage allocation and specification are regulated by Sphingosine-1-phosphate signaling” PLoS Biol. 15(3): e2000949

P. Pallaki, I. Georganta, I. Serafimidis, M. Papakonstantinou, A. Agalou, S. Koutloglou, A. Symeonof, A. Tserga, E. Papadimitriou, V. Papanikolaou, D. Thomaidou, M. Gaitanou and Z. Georgoussi (2017) “A novel regulatory role of RGS4 in STAT5B activation, neurite outgrowth and neuronal differentiation” Neuropharmacology 117(1), p.408-21

V. Anastasiou, E. Ninou, D. Alexopoulou, J. Stertmann, A.Muller, A. Dahl, M. Solimena, S. Speier, I. Serafimidis* and A. Gavalas* (2016) “Aldehyde dehydrogenase activity is necessary for β cell development and functionality in mice” Diabetologia 59(1), p.139-50
(*corresponding authors)

M. Ioannou, I. Serafimidis, L. Sussel, L. Arnes, S. Singh, V. Vasiliou and A. Gavalas (2013) “Aldh1b1 is a potential pluripotency gene in pancreas progenitor pools” Dev. Biol. 374(1), p.153-63

I. Serafimidis, S. Heximer, D. Beis and A. Gavalas (2011) “GPCR signalling and S1P play a phylogenetically conserved role in endocrine pancreas morphogenesis” Mol. Cell Biol. 31(22), p.4442-53

M. Kapasa, I. Serafimidis, A. Gavalas and S. Kossida (2008) “Identification of phylogenetically conserved enhancer elements implicated in pancreas development in the WISP1 and CTGF orthologs” Genomics  92(5), p.301-8

I. Serafimidis, I. Rakatzi, V. Episkopou, M. Gouti and A. Gavalas (2008) “Novel effectors of directed and ngn3-mediated differentiation of mouse embryonic stem cells into endocrine pancreas progenitors” Stem Cells 26(1), p.3-16

B. Nuñez-Corcuera, I. Serafimidis, E. Arias-Palomo, A. Rivera-Calzada and T. Suárez (2008) “A new protein carrying a NmrA-like domain is required for cell differentiation and development in Dictyostelium”  Dev.Biol. 321(2), p.331-42

I. Serafimidis, G. Bloomfield, J. Skelton, A. Ivens and R.R. Kay (2007) “A new environmentally-resistant cell type in Dictyostelium” Microbiology  153(2), p619-30

I. Serafimidis and R.R. Kay (2005) “New prestalk and prespore inducing signals in Dictyostelium” Dev. Biol. 282(2), p.432-441
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