Publications

Thompson J, Doxakis E, Pinon LG, Strachan P, Buj-Bello A, Wyatt S, Buchman VL, Davies AM (1998) GFRalpha-4, a new GDNF family receptor. Mol. Cell. Neurosci. 11: 117-126.

Forgie A, Doxakis E, Buj-Bello A, Wyatt S, Davies AM (1999) Differences and developmental changes in the responsiveness of PNS neurons to GDNF and neurturin. Mol. Cell. Neurosci. 13: 430-440.

Wyatt S, Middleton G, Doxakis E, Davies AM (1999) Selective regulation of TrkC expression by NT3 in the developing peripheral nervous system. J. Neurosci. 19: 6559-6570.

Doxakis E, Wyatt S, Davies AM (2000) Depolarisation causes reciprocal changes in GFR(alpha)-1 and GFR(alpha)-2 receptor expression and shifts responsiveness to GDNF and neurturin in developing neurons. Development. 127: 1477-1487.

Oliver Schmidt, Doxakis E, Davies AM (2002) Macrophage-stimulating protein is a neurotrophic factor for embryonic chicken hypoglossal motoneurons. Eur. J. Neurosci. 15: 1-9.

Doxakis E, Huang EJ, Davies AM (2004) Homeodomain-interacting protein kinase-2 regulates apoptosis in developing sensory and sympathetic neurons. Curr. Biol. 14:1761-1765.

Wiggins AK, Wei G, Doxakis E, Wong C, Tang AA, Zang K, Luo EJ, Neve RL, Reichardt LF, Huang EJ (2004) Interaction of Brn3a and HIPK2 mediates transcriptional repression of sensory neuron survival. J. Cell Biol. 167: 257-267.

Doxakis E and Davies AM (2005) Retinoic acid negatively regulates GDNF and neurturin receptor expression and responsiveness in embryonic chicken sympathetic neurons. Mol. Cell. Neurosci. 29:617-627.

Pape M1, Doxakis E1, Duong CV, Davies AM, Geissen M, Rohrer H (2008) A function for the calponin family member NP25 in neurite outgrowth. Dev. Biol. 321: 434-43.  1equal first authors.

Doxakis E Howard L, Rohrer H and Davies AM (2008) Hand transcription factors are required for postnatal sympathetic neuron survival. EMBO Rep. 9: 1041-7.

Doxakis E (2010) Post-transcriptional regulation of alpha-synuclein expression by miR-7 and miR-153. JBC, 285:12726-34.

Paschou M, Paraskevopoulou MD, Vlachos IS, Koukouraki P, Hatzigeorgiou AG, Doxakis E (2012). miRNA regulons associated with synaptic function. PLoS One, 7: e46189.

Paschou M and Doxakis E (2012) Neurofibromin is a direct miRNA target in the nervous system. PLoS One, 7: e46773.

Schouten M, Aschrafi A, Bielefeld P, Doxakis E, Fitzsimons CP (2013) microRNAs and the regulation of neuronal plasticity under stress conditions. Neurosc., 241: 188-205.

Doxakis E (2013) Principles of miRNA-target regulation in metazoan models. Int. J. Mol. Sci., 14:16280-302.

Doxakis E (2014) RNA binding proteins: a common denominator of neuronal function and dysfunction. Neurosci. Bull., 30: 610-26.

Fragkouli A, Doxakis E (2014) miR-7 and miR-153 protect neurons against MPP+- induced cell death via upregulation of mTOR pathway. Front. Cell. Neurosci., 8: 182.

Koukouraki P, Doxakis E (2016) Constitutive translation of human alpha-synuclein is mediated by the 5’ untranslated region. Open Biology, 6: 160022.

Fragkouli A, Koukouraki P, Vlachos IS, Paraskevopoulou MD, Hatzigeorgiou AG, Doxakis E (2017) Neuronal ELAVL proteins utilize AUF-1 as a co-partner to induce neuron-specific alternative splicing of APP. Sci. Rep., 7: 44507.

Ravanidis S, Kattan FG, Doxakis E (2018) Unraveling the pathways to neuronal homeostasis and disease: mechanistic insights into the role of RNA-binding proteins and associated factors. Int. J. Mol. Sci., 19: 2280.

Ravanidis S, Bougea A, Papagiannakis N, Maniati M, Koros C, Simitsi AM, Bozi M, Pachi I, Stamelou M, Paraskevas GP, Kapaki E, Moraitou M, Michelakakis H, Stefanis L, Doxakis E (2020) Circulating brain-enriched microRNAs for detection and discrimination of idiopathic and genetic Parkinson's disease. Mov. Disord., 35: 457‐467.

Paschou M, Maier L, Papazafiri P, Selescu T, Dedos SG, Babes A, Doxakis E (2020) Neuronal microRNAs modulate TREK two-pore domain K+ channel expression and current density. RNA Biol., 17: 651‐662.

Doxakis E (2020) Cell-free microRNAs in Parkinson's disease: potential biomarkers that provide new insights into disease pathogenesis. Ageing Res. Rev., 58: 101023.

Ravanidis S and Doxakis E (2020) RNA binding proteins implicated in mitochondrial damage and mitophagy. Front. Cell. Dev Biol., 8: 372.

Doxakis E (2020) Therapeutic antisense oligonucleotides for movement disorders. Med. Res. Rev., Jul 13.

Ravanidis S, Bougea A, Papagiannakis N, Koros C, Simitsi AM, Bozi M, Pachi I, Breza M, Stefanis L, Doxakis E (2020) Validation of differentially expressed brain-enriched microRNAs in the plasma of PD patients. Ann. Clin. Transl. Neurol., 7:1594-1607.

Ravanidis S, Bougea A, Karampatsi D, Papagiannakis N, Maniati M, Stefanis L, Doxakis E (2021) Differentially expressed circular RNAs in peripheral blood mononuclear cells of patients with Parkinson's disease. Mov. Disord., 36:1170-1179.

Ravanidis S, Grundler F, de Toledo FW, Dimitriou E, Tekos F, Skaperda Z, Kouretas D, Doxakis E (2021) Fasting-mediated metabolic and toxicity reprogramming impacts circulating microRNA levels in humans. Food Chem. Toxicol. 152:112187.

Doxakis E (2021) Insights into the multifaceted role of circular RNAs: implications for Parkinson's disease pathogenesis and diagnosis. NPJ Parkinsons Dis., in press.

Gourdomichali O, Zonke K, Kattan FG, Makridakis M, Kontostathi G, Vlahou A, Doxakis E (2022) In Situ Peroxidase Labeling Followed by Mass-Spectrometry Reveals TIA1 Interactome. Biology (Basel). 11: 287.

Naki M, Gourdomichali O, Zonke K, Kattan FG, Makridakis M, Kontostathi G, Vlahou A, Doxakis E (2022) APEX2-Mediated Proximity Labeling Resolves the DDIT4-Interacting Proteome. Int. J. Mol. Sci., 23: 5189.

Paschou M, Papazafiri P, Charalampous C, Zachariadis M, Dedos SG, Doxakis E (2022) Neuronal microRNAs safeguard ER Ca2+ homeostasis and attenuate the unfolded protein response upon stress. Cell. Mol. Life Sci., 79: 373.