BRFAA - Biomedical Research Foundation Academy Of Athens
Biomedical Research Foundation Academy Of AthensAcademy Of Athens

Publications

Mitochondrial Oxidative Damage Underlies Regulatory T Cell Defects in Autoimmunity
Themis Alissafi, Lydia Kalafati, Maria Lazari, Anastasia Filia, Ismini Kloukina, Maria Manifava, Jong-Hyung Lim, Vasileia Ismini Alexaki, Nicholas T Ktistakis, Triantafyllos Doskas, George A Garinis, Triantafyllos Chavakis, Dimitrios T Boumpas, Panayotis Verginis
Cell Metab. 2020 Jul 22;S1550-4131(20)30359-4. doi: 10.1016/j.cmet.2020.07.001.

Fabrication of a 3D microfluidic cell culture device for bone marrow-on-a-chip. Micro and Nano Engineering
Kefallinou D, Grigoriou M, Boumpas DT, Gogolides E, Tserepi A. 
2020/11/01/ 2020;9:100075.

Mitochondrial Oxidative Damage Underlies Regulatory T Cell Defects in Autoimmunity
Themis Alissafi, Lydia Kalafati, Maria Lazari, Anastasia Filia, Ismini Kloukina, Maria Manifava, Jong-Hyung Lim, Vasileia Ismini Alexaki, Nicholas T Ktistakis, Triantafyllos Doskas, George A Garinis, Triantafyllos Chavakis, Dimitrios T Boumpas, Panayotis Verginis
Cell Metab. 2020 Jul 22;S1550-4131(20)30359-4. doi: 10.1016/j.cmet.2020.07.001.

IFNα Impairs Autophagic Degradation of mtDNA Promoting Autoreactivity of SLE Monocytes in a STING-Dependent Fashion
Katerina Gkirtzimanaki, Eleni Kabrani, Dimitra Nikoleri, Alexander Polyzos, Athanasios Blanas, Prodromos Sidiropoulos, Antonis Makrigiannakis, George Bertsias, Dimitrios T Boumpas, Panayotis Verginis
Cell Rep. 2018 Oct 23;25(4):921-933.e5. doi: 10.1016/j.celrep.2018.09.001.

Transcriptome Reprogramming and Myeloid Skewing in Haematopoietic Stem and Progenitor Cells in Systemic Lupus Erythematosus
Maria Grigoriou, Aggelos Banos, Anastasia Filia, Pavlos Pavlidis, Stavroula Giannouli, Vassiliki Karali, Dionysis Nikolopoulos, Antigone Pieta, George Bertsias, Panayotis Verginis, Ioannis Mitroulis, Dimitrios T Boumpas
Ann Rheum Dis.2020 Feb;79(2):242-253. doi: 10.1136/annrheumdis-2019-215782. Epub 2019 Nov 28.

Evolving Phenotype of Systemic Lupus Erythematosus in Caucasians: Low Incidence of Lupus Nephritis, High Burden of Neuropsychiatric Disease and Increased Rates of Late-Onset Lupus in the 'Attikon' Cohort
D Nikolopoulos, M Kostopoulou, A Pieta, T Karageorgas, D Tseronis, K Chavatza, S Flouda, P Rapsomaniki, A Banos, E Kremasmenou, V Tzavara, P Katsimbri, A Fanouriakis, D T Boumpas
Lupus.2020 Apr;29(5):514-522. doi: 10.1177/0961203320908932. Epub 2020 Feb 27.

Combined genetic and transcriptome analysis of patients with SLE: distinct, targetable signatures for susceptibility and severity.
Panousis NI, Bertsias GK, Ongen H, Gergianaki I, Tektonidou MG, Trachana M, Romano-Palumbo L, Bielser D, Howald C, Pamfil C, Fanouriakis A, Kosmara D, Repa A, Sidiropoulos P, Dermitzakis ET, Boumpas DT
Ann Rheum Dis. 2019 Jun 5. pii: annrheumdis-2018-214379. doi: 10.1136/annrheumdis-2018-214379.

REDD1/autophagy pathway promotes thromboinflammation and fibrosis in human systemic lupus erythematosus (SLE) through NETs decorated with tissue factor (TF) and interleukin-17A (IL-17A).
Frangou E, Chrysanthopoulou A, Mitsios A, Kambas K, Arelaki S, Angelidou I, Arampatzioglou A, Gakiopoulou H, Bertsias GK, Verginis P, Ritis K, Boumpas DT.

Sexual dimorphism in SLE: above and beyond sex hormones.
EAA Christou, A Banos, D Kosmara, GK Bertsias and DT Boumpas
Lupus. 2019 Jan;28(1):3-10. doi: 10.1177/0961203318815768. Epub 2018 Dec 1.

Combined genetic and transcriptome analysis of patients with SLE: distinct, targetable signatures for susceptibility and severity.
Panousis NI, Bertsias GK, Ongen H, Gergianaki I, Tektonidou MG, Trachana M, Romano-Palumbo L, Bielser D, Howald C, Pamfil C, Fanouriakis A, Kosmara D, Repa A, Sidiropoulos P, Dermitzakis ET, Boumpas DT
Ann Rheum Dis. 2019 Jun 5. pii: annrheumdis-2018-214379. doi: 10.1136/annrheumdis-2018-214379.

Identification of novel microRNA signatures linked to human lupus disease activity and pathogenesis: miR-21 regulates aberrant T cell responses through regulation of PDCD4 expression.
Stagakis E, Bertsias G, Verginis P, Nakou M, Hatziapostolou M, Kritikos H, Iliopoulos D, Boumpas DT. 
Ann Rheum Dis. 2011 Aug;70(8):1496-506.

Elimination of granulocytic myeloid-derived suppressor cells in lupus-prone mice due to ROS-dependent extracellular trap formation.
Vlachou K, Mintzas K, Glymenaki M, Ioannou M, Papadaki G, Bertsias GK, Sidiropoulos P, Boumpas DT, Verginis P. 
Arthritis Rheumatol. 2016 Feb;68(2):449-61

MicroRNA analysis of renal biopsies in human lupus nephritis demonstrates upregulated miR-422a driving reduction of kallikrein-related peptidase 4.
Krasoudaki E, Banos A, Stagakis E, Loupasakis K, Drakos E, Sinatkas V, Zampoulaki A, Papagianni A, Iliopoulos D, Bertsias G, Boumpas DT. 
Nephrol Dial Transplant. 2016 Oct;31(10):1676-86.

Neutrophil extracellular traps exacerbate Th1-mediated autoimmune responses in rheumatoid arthritis by promoting DC maturation.
Papadaki G, Kambas K, Choulaki C, Vlachou K, Drakos E, Bertsias G, Ritis K, Boumpas DT, Thompson PR, Verginis P, Sidiropoulos P.
Eur J Immunol. 2016 Nov;46(11):2542-2554.

Full list of Publications on Pubmed