Publications

Below is a list of selected publications:

Fragkos Μ, Anagnou ΝP, Tubb J, and Emery DW: Use of hereditary persistence of fetal hemoglobin 2 enhancer to increase the expression of oncoretrovirus vectors for human gene therapy. Gene Ther 12:1591-1600, 2005.

Pappa KI, and Anagnou NP: Emerging issues of the expression profiling technologies for the study of gynecological cancer. Am J Obstet Gynecol 193:908-918, 2005

Lygnos MC, Pappa KI, Papadaki HA, Relakis C, Koumantakis E, Anagnou NP, and Eliopoulos GD. Changes in maternal plasma levels of VEGF, bFGF, TGF-beta1, ET-1 and sKL during uncomplicated

Pappa KI, Vlachos G, Theodora M, Roubelaki M, Angelidou K, Antsaklis A. Intermediate metabolism in association with the amino acid profile during the third trimester of normal pregnancy and diet-controlled gestational diabetes. Am. J. of Obster Gynec. 65.e1-65.e5 2007.

Roubelakis MG, Pappa KI, Bitsika V, Zagoura D, Vlahou A., Papadaki H, Antsaklis A, and Anagnou NP. Isolation, phenotypic, molecular and proteomic characterization of human mesenchymal stem cells (MSCs) derived from amniotic fluid: comparison to bone marrow. Stem Cells and Dev. 16: 931-952,

Makridakis M, Gagos S, Petrolekas A, Roubelakis MG, Bitsika V, Stravodimos K, Pavlakis K, Anagnou NP, Coleman J, and Vlahou A. Chromosomal and proteome analysis of a new T24-based cell line model for aggressive bladder cancer. Proteomics 9:287-298, 2009.

Pappa KI, and Anagnou NP. Novel sources of fetal stem cells: where do they fit on the developmental continuum? Regen Med 4:423-433, 2009.

Roubelakis MG, Zotos P, Papachristoudis G, Michalopoulos I, Pappa KI, Anagnou NP and Kossida S. Human microRNA target analysis and gene ontology clustering by GOmir, a novel stand-alone application. BMC Bioinformatics 10 (Suppl 6):S20, 2009.

Gazouli M, Katsantoni E, Kosteas T, and Anagnou NP. Persistent fetal γ-globin expression in adult transgenic mice following deletion of two silencer elements located 3' to the human Aγ-globin gene. Mol Med 15:415-424, 2009.

Spyrou P, Phylactides M, Lederer CW, Kithreotis L, Kirri A, Christou S, Kkolou E, Kanavakis E, Anagnou NP, Stamatoyannopoulos G, and Kleanthous M. Compounds of the anthracycline family of antibiotics elevate human gamma-globin expression both in erythroid cultures and in a transgenic mouse model. Blood Cells Mol Dis 44:100-106, 2010.

Franke A, Balschun T, Sina C, Ellinghaus D, H?sler R, Mayr G, Albrecht M, Witting M, Buchert E, Nikolaus S, Gieger C, Wichman HE, Sventoraityte J, Kupcinskas L, Onnie CM, Gazouli M, Anagnou NP, Strachan D, McArdle WL, Mathew CG, Rutgeerts P, Vermeire S, Vatn MH and the IBSEN study group, Krawczak M, Rosenstiel P, Karlsen TH, and Schreiber, S. Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL). Nat Genetics 42:292-294, 2010.

Makridakis M, Roubelakis MG, Bitsika V, Dimuccio V, Samiotaki M, Kossida S, Panayotou G, Coleman J, Candiano G, Anagnou NP, and Vlahou A. Analysis of secreted proteins for the study of bladder cancer cell aggressiveness. J Proteome Res May 13, 2010 [Epub ahead of print].

Pappa KI, Gazouli M, Economou K, Daskalakis G, Anastasiou E, Anagnou NP, and Antsaklis A. Gestational diabetes mellitus shares polymorphisms of genes associated with insulin resistance and type 2 diabetes in the Greek population. Gynecol Endocrinol Jun 14, 2010 [Epub ahead of print].

Pappa KI, Roubelakis M, Vlachos G, Marinopoulos S, Zissou A, Anagnou NP, and Antsaklis A. Variable effects of maternal and paternal-fetal contribution to the risk of preeclampsia combining GSTP1, eNOS and LPL gene polymorphisms. J Matern Fetal Neonatal Med Sep 14, 2010 [Epub ahead of print].

Papanikolaou E, and Anagnou NP. Major challenges for gene therapy of thalassemia and sickle cell disease. Curr Gene Ther 10:404-412, 2010.

Roubelakis MG, Bitsika V, Zagoura D, Trohatou O, Pappa KI, Makridakis M, Antsaklis A, Vlahou A, and Anagnou NP. In vitro an in vivo properties of distinct populations of amniotic fluid mesenchymal progenitor cells. J Cell Mol Med 2010 Sep 27. doi: 10.1111/j.1582-4934.2010.01176.x. [Epub ahead of print].

Gazouli M, Roubelakis MG, Theodoropoulos GE, Papailiou J, Vaiopoulou A, Nikiteas N and Anagnou NP. 2011. OCT4 Spliced Variant OCT4B1 is Expressed in Human Colorectal Cancer. Molecular Carcinogenesis  Apr 7. doi: 10.1002/mc.20773. [Epub ahead of print]

Zagoura D, Roubelakis ΜG*, Bitsika V, Trohatou O, Pappa KI, Kapelouzou A, Antsaklis A and Anagnou N.P. 2011. Therapeutic potential of human amniotic fluid mesenchymal stem cells and their secreted molecules into mice with acute hepatic failure. Gut Oct 13. Gut. 2012 Jun;61(6):894-906. Epub 2011 Oct 13

Bitsika V, Roubelakis MG, Zagoura D, Trohatou O, Makridakis M, Pappa KI, Marini FC, Vlahou A and Anagnou NP. 2011. Human Amniotic Fluid-Derived Mesenchymal Stem Cells as Therapeutic Vehicles: A Novel Approach for the Treatment of Bladder Cancer. Stem Cells and Dev Oct 13. 2012 May 1;21(7):1097-111. Epub 2011 Oct 11.

Drakopoulou E, Papanikolaou E, Anagnou NP. The Ongoing Challenge of Hematopoietic Stem Cell-Based Gene Therapy for β-Thalassemia. Stem Cells Int. 2011;2011:987980. Epub 2011 Nov 13.

Pappa KI, Jacob-Hirsch J, Vlachos GD, Christodoulou I, Partsinevelos G, Amariglio N, Markaki S, Antsaklis A, Anagnou NP.
Expression profiling of vulvar carcinoma: clues for deranged extracellular matrix remodeling and effects on multiple signaling pathways combined with discrete patient subsets. Transl Oncol. 2011 Oct;4(5):301-13. Epub 2011 Oct 1.

Zoidakis J, Makridakis M, Panagiotis Zerefos G., Bitsika V, Esteban S, Stravodimos K, Anagnou NP, Roubelakis MG+, Sanchez-Carbayo M+, Vlahou A. 2011. Fractionation of urine proteome by metal affinity chromatography reveals profilin as a potential biomarker for bladder cancer aggressiveness. Mol Cell Proteomics. 2012 Apr;11(4):M111.009449. Epub 2011 Dec 8.

Roubelakis MG, Trohatou O, Anagnou NP. 2012.  Amniotic fluid and amniotic membrane stem cells: Marker discovery, Review, Stem Cells International  :107836. Epub 2012 Jun 3.

Zotos P, Roubelakis MG, Anagnou NP and Kossida S. 2012. Overview of microRNA target analysis tools. Review, Current Bioinformatics (in press).