Biomedical Research Foundation Academy Of AthensAcademy Of Athens
Scientific Personnel

Konstantinos Konstantinos Avgoustakis, PhD
University Faculty, Affiliated Investigator

Telephone : +30 210 6597 475
e-mail :

Center :

Clinical, Experimental Surgery & Translational Research

Brief Bio

1985: Bsc in Pharmacy, University of Thessaloniki, Greece
1991: Ph.D. in Pharmaceutics/Quality Control of Drugs, University of Thessaloniki, Greece
1992: Ph.D. in Pharmaceutical Technology, London University, UK

2008 – today: Associate Professor in University of Patras, Department of Pharmacy, Pharmaceutics Lab., Rio 26 500, Patras, Greece
2000 - 2008: Assistant Professor in University of Patras, Department of Pharmacy, Pharmaceutics Lab., Rio 26 500, Patras, Greece
1994-2000: Lecturer in the Department of Pharmacy, University of Patras.
1993-1994 : Research assistant in Institute of Radioisotopes and Radiodiagnostic Products, NCSR "Demokritos", Athens, Greece

• Pharmaceutics and Biopharmaceutics
• Pharmaceutical Nanotechnlology

a) Targeted delivery of anticancer drugs based on i) biodegradable, polymeric, long-circulating  (“stealth”)  nanoparticles and  ii) magnetic hybrid nanoparticles,
b) Development of novel prophylactic or therapeutic vaccines based on biodegradable and biocompatible, polymeric nano- and micro-particles,
c) Development of formulations for the efficient delivery of drugs with limited aqueous solubility
d) Supramolecular carbon structures (fullerenes, graphenes) in controlled drug delivery

Research papers : 53
Articles in Biomedical Encyclopedia: 1
Presentations in International Scientific Conferences: 40
Patents: 2 European Patents
Index h (Coogle Scholar): 21
Non-self citations: 1434

Selected Publications

George E. Magoulas, Marina Bantzi, Danai Messari, Efstathia Voulgari, Chrisostomi Gialeli, Despoina Barbouri, Athanassios Giannis, Nikos K. Karamanos, Dionissios Papaioannou, and Konstantinos Avgoustakis, Synthesis and Εvaluation of Αnticancer Αctivity in Cells of Novel Stoichiometric Pegylated Fullerene-Doxorubicin Conjugates, Pharmaceutical Research, in press DOI 10.1007/s11095-014-1566-1.

Giorgio Zoppellaro, Argiris Kolokithas-Ntoukas, Katerina Polakova, Jiri Tucek, Radek Zboril, George Loudos, Eirini Fragogeorgi, Clemens Diwoky, Katerina Tomankova, Konstantinos Avgoustakis, Dimitris Kouzoudis, and Aristides Bakandritsos, Theranostics of Epitaxially Condensed Colloidal Nanocrystal Clusters through a Soft Biomineralization Route, Chemistry of Materials 26 (2014) 2062-2074.

Athanassios Giarmoukakis, Georgios Labiris, Haris Sideroudi, Zinovia Tsimali, Nefeli Koutsospyrou, Konstantinos Avgoustakis, Vassilios Kozobolis, Biodegradable nanoparticles for controlled subconjunctival delivery of latanoprost acid: In vitro and in vivo evaluation. Preliminary results, Experimental Eye Research 112 (2013) 29-36.

G.E. Magoulas, T. Garnelis, C.M. Garnelis, C.M. Athanassopoulos, D. Papaioannou, G. Mattheolabakis, K. Avgoustakis, D. Hatzipavlou-Litina, Synthesis and antioxidative/anti-inflammatory activity of novel fullerene-polyamine conjugates, Tetrahedron, 68 (2012) 7041-7049.

Aristides Bakandritsos, Aristeidis Papagiannopoulos, Eleni N. Anagnostou, Konstantinos Avgoustakis, Radek Zboril, Stergios Pispas, Jiri Tucek, Vasyl Ryukhtin, Nikolaos Bouropoulos, Argiris Kolokithas-Ntoukas, Theodore A. Steriotis, Uwe Keiderling and Frank Winnefeld, Merging High Doxorubicin Loading with Pronounced Magnetic Response and Bio-repellent Properties in Hybrid Drug Nanocarriers, Small, 8 (2012) 2381-2393.

Mingguang Li, Zoi Panagi, Konstantinos Avgoustakis, Joshua Reineke, Physiologically Based Pharmacokinetic modeling of PLGA Nanoparticles with varied mPEG content, Int. J. Nanosc., 2012, 7, 1345-56.

Zacharoula Iatridi, George Mattheolabakis, Konstantinos Avgoustakis, and Constantinos Tsitsilianis, Self-assembly and drug delivery studies of pH/thermo-sensitive polyampholytic (A-co-B)-b-C-b-(A-co-B) segmented terpolymers, Soft Matter, 2011, 7, 11160-11168.

Aristides Bakandritsos, George Mattheolabakis, George Chatzikyriakos, Tamas Szabo, Vasilis Tzitzios, Dimitris Kouzoudis, Stelios Couris, Konstantinos Avgoustakis, “Doxorubicin Nanocarriers Based on Magnetic Colloids with a bio-Polyelectrolyte Corona and High non-linear Optical Response: Synthesis, Characterization and Properties”, Advanced Functional Materials, 21, 2011, 1465-1475.

A.A. Vassiliou, S. A. Papadimitriou, D. N. Bikiaris, G. Mattheolabakis and K. Avgoustakis, “Facile synthesis of polyester-PEG triblock copolymers and preparation of amphiphilic nanoparticles as drug carriers”, J. Control. Rel., 148 , 2010, 388-395.

George Mattheolabakis, George Lagoumintzis, Zoi Panagi, Evangelia Papadimitriou, Charalambos D. Partidos, Konstantinos Avgoustakis, “Immune stimulation after transcutaneous delivery with antigen-loaded PLA nanoparticles” Int. J. of Pharm., 385, 2010, 187-193.


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