Biomedical Research Foundation Academy Of AthensAcademy Of Athens
Scientific Personnel

Alexandros Alexandros Stratigos, PhD
University Faculty, Affiliated Investigator

e-mail :

Center :

Clinical, Experimental Surgery & Translational Research

Brief Bio

Alexander J. Stratigos, MD is Professor of Dermatology-Dermatology at the Department of Dermatology-Venereology, University of Athens Medical School, Andreas Sygros Hospital (Athens, Greece). He earned his medical degree from the University of Athens and completed an internship in Internal Medicine and a residency in Dermatology at the Massachusetts General Hospital, Harvard Medical School (Boston, United States) before returning as faculty at the University of Athens School of Medicine. He directs the Dermato-Oncology Center and Melanoma Unit at A. Sygros Hospital and has led as local PI several multicenter clinical trials on biologic agents in psoriasis and hedgehog inhibitors and checkpoint inhibitors in non-melanoma skin cancer. His clinical interests include melanoma and skin cancer, psoriasis, and cutaneous photosensitivity. He also directs the Molecular Biology Laboratory at A. Sygros Hospital with a primary focus on the genetics of melanoma and skin cancer and with on-going collaborations with the NCI/USA (Melanostrum Consortium), MGH/Broad Institute, BioGenomel Consortium and the Harvard School of Public Health. His research work has been funded by the Aristeia Program, the Synergasia Program and the NCI. Dr. Stratigos serves at the editorial board of the Journal of the American Academy of Dermatology, the SkinMed Journal: Dermatology for the Clinician and the Journal of the Hellenic Society of Dermatology-Venerology. He is the author of over 200 publications in international peer-reviewed medical journals and has co-authored 7 textbook chapters and two books. Dr. Stratigos has held administrative positions in several professional societies, including the European Academy of Dermatology and Venereology (member of the Board of Directors until 2012, currently Chairman of the Project Proposal Review Committee), the European Association of Dermato-Oncology (Vice-President), the International Dermoscopy Society, the American Academy of Dermatology, the Hellenic Society of Dermatology-Venereology (Treasurer) and the Hellenic Society for Melanoma Research (President-elect). Since 2012, Dr. Stratigos has an appointment as Visiting Scientist at the Wellman Laboratories of Photomedicine of the Massachusetts General Hospital (Boston, USA). During June 2010 until June 2013 he was a member of the National Ethics Committee (Greece).

Selected Publications

Kypreou KP, Stefanaki I, Antonopoulou K, Karagianni F, Ntritsos G, Zaras A, Nikolaou V, Kalfa I, Chasapi V, Polydorou D, Gogas H, Spyrou GM, Bertram L, Lill CM, Ioannidis JP, Antoniou C, Evangelou E, Stratigos AI. Prediction of Melanoma Risk in a Southern European Population Based on a Weighted Genetic Risk Score. J Invest Dermatol. 2016 Mar;136(3):690-5.

Soura E, Eliades PJ, Shannon K, Stratigos AJ, Tsao H. Hereditary melanoma: Update on syndromes and management: Emerging melanoma cancer complexes and genetic counseling. J Am Acad Dermatol. 2016 Mar;74(3):411-20. doi: 10.1016/j.jaad.2015.08.037.

Stratigos A, Garbe C, Lebbe C, Malvehy J, del Marmol V, Pehamberger H, Peris K, Becker JC, Zalaudek I, Saiag P, Middleton MR, Bastholt L, Testori A, Grob JJ; European Dermatology Forum (EDF); European Association of Dermato-Oncology (EADO); European Organization for Research and Treatment of Cancer (EORTC). Diagnosis and treatment of invasive squamous cell carcinoma of the skin: European consensus-based interdisciplinary guideline. Eur J Cancer. 2015 Sep;51(14):1989-2007. doi: 10.1016/j.ejca.2015.06.110. Epub 2015 Jul 25.

Law MH, Bishop DT, Lee JE, Brossard M, Martin NG, Moses EK, Song F, Barrett JH, Kumar R, Easton DF, Pharoah PD, Swerdlow AJ, Kypreou KP, Taylor JC, Harland M, Randerson-Moor J, Akslen LA, Andresen PA, Avril MF, Azizi E, Scarrà GB, Brown KM, Dȩbniak T, Duffy DL, Elder DE, Fang S, Friedman E, Galan P, Ghiorzo P, Gillanders EM, Goldstein AM, Gruis NA, Hansson J, Helsing P, Hočevar M, Höiom V, Ingvar C, Kanetsky PA, Chen WV; GenoMEL Consortium; Essen-Heidelberg Investigators; SDH Study Group; Q-MEGA and QTWIN Investigators; AMFS Investigators; ATHENS Melanoma Study Group, Landi MT, Lang J, Lathrop GM, Lubiński J, Mackie RM, Mann GJ, Molven A, Montgomery GW, Novaković S, Olsson H, Puig S, Puig-Butille JA, Qureshi AA, Radford-Smith GL, van der Stoep N, van Doorn R, Whiteman DC, Craig JE, Schadendorf D, Simms LA, Burdon KP, Nyholt DR, Pooley KA, Orr N, Stratigos AJ, Cust AE, Ward SV, Hayward NK, Han J, Schulze HJ, Dunning AM, Bishop JA, Demenais F, Amos CI, MacGregor S, Iles MM. Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma. Nat Genet. 2015 Sep;47(9):987-95.

Antonopoulou K, Stefanaki I, Lill CM, Chatzinasiou F, Kypreou KP, Karagianni F, Athanasiadis E, Spyrou GM, Ioannidis JP, Bertram L, Evangelou E, Stratigos AJ. Updated field synopsis and systematic meta-analyses of genetic association studies in cutaneous melanoma: the MelGene database. J Invest Dermatol. 2015 Apr;135(4):1074-9. doi: 10.1038/jid.2014.491. Epub 2014 Nov 19.

Dessinioti C, Sypsa V, Kypreou K, Dimisianos G, Kodela E, Nikolaou V, Antoniou C, Stratigos AJ. A case-control study of MC1R variants in Greek patients with basal cell carcinoma: increased risk independently of pigmentary characteristics. Exp Dermatol. 2015 Jun;24(6):476-8.

Masouri S, Stefanaki I, Kypreou KP, Kodela E, Bethimoutis G, Ntritsos G, Evangelou E, Stratigos AJ, Antoniou C. Replication of risk variants for psoriasis in a Southern European case-control study: correlation with clinical subphenotypes. Br J Dermatol. 2015 Aug;173(2):552-4.

Stefanaki I, Panagiotou O, Kodela E, Gogas H, Kypraiou K, Nikolaou V, Plaka M, Kalfa, Antoniou C,  Ioannidis JP,  Evangelou E,  Stratigos AJ. Replication and predictive value of SNPs associated with melanoma and pigmentation traits in a Southern European case-control study, PLoS One. 2013;8(2):e55712.

Nikolaou V, Kang X, Stratigos A, Gogas H, Latorre MC, Gabree M, Plaka M, Njauw C, Kypreou K, Mirmigi I, Stefanaki I, Tsao H. Comprehensive mutational analysis of CDKN2A and CDK4 in greek patients with cutaneous melanoma. Br J Dermatol. 2011;165(6):1219-22.

Chatzinasiou F, Lill CM, Kypreou K, Stefanaki I, Nicolaou V, Spyrou G, Evangelou E,. Roehr JT, Kodela E, Katsambas A, Tsao H, Ioannidis JPA, Bertram L, Stratigos AJ. Comprehensive Field Synopsis and Systematic Meta-analyses of Genetic Association Studies in Cutaneous Melanoma. J Natl Cancer Inst. 2011 Aug 17;103(16):1227-35.

Nikolaou VA, Sypsa V, Stefanaki I, Gogas H, Papadopoulos O, Polydorou D, Plaka M, Tsoutsos D, Dimou A, Mourtzoukou E, Korfitis V, Hatziolou E, Antoniou C, Hatzakis A, Katsambas A, Stratigos AJ. Risk associations of melanoma in a Southern European population: results of a case/control study. Cancer Causes Control 2008;19:671-9.

Stratigos AJ, Dimisianos G, Nikolaou V, Poulou M, Sypsa V, Stefanaki I, Papadopoulos O, Polydorou D, Plaka M, Christofidou E, Gogas H, Tsoutsos D, Kastana O, Antoniou C, Hatzakis A, Kanavakis E, Katsambas AD. Melanocortin Receptor-1 Gene Polymorphisms and the Risk of Cutaneous Melanoma in a Low-Risk Southern European Population. J Invest Dermatol 2006;126: 1842-9.


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